Persson, Sara
(2013).
The wild male mink as a sentinel for
endocrine-disrupting chemicals and
reproductive toxicity.
Diss. (sammanfattning/summary)
Uppsala :
Sveriges lantbruksuniv.,
Acta Universitatis Agriculturae Sueciae, 1652-6880
; 2013:65
ISBN 978-91-576-7868-3
eISBN 978-91-576-7869-0
[Doctoral thesis]
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PDF
379kB |
Abstract
Increasing evidence indicates that pollutants may affect the hormone system of humans and wildlife. These endocrine-disrupting chemicals are related to an increased risk of a
variety of diseases and disorders, including adverse effects on the reproductive system. By using a sentinel wildlife species, an early warning of adverse health effects due to pollutants in the environment may be provided. This is also relevant for humans, as wildlife and humans can be exposed to similar mixtures of pollutants.
With this in mind, the aim of this thesis is to investigate the possibility of establishing the wild mink (Neovison vison) as a sentinel species in Sweden, for both exposure to pollutants and effects of pollutants on the reproductive system. Mink were collected from local hunters and necropsies were performed focusing on the male reproductive system. The collected mink provided an insight in how to handle the variation in data due to sample season, age and nutritional status. These factors significantly influenced many, but not all, of the concentrations of chlorinated,
brominated and perfluorinated compounds and also some reproductive organ variables. In addition, the results offer information on how to optimize the design of future
studies, and some baseline data for reproductive organ measurements were compiled. Considerable concentrations of PCBs were found in some areas and the concentrations
of PFOS were among the highest ever recorded in mink. Associations were found between measurements on the reproductive organs and pollutant concentrations. The
anogenital distance was inversely associated with concentrations of some perfluoroalkyl acids and DDE. Several associations were also found between some
PCB congeners and measurements on the penis and baculum.
In conclusion, the wild mink males may serve as an indicator for environmental exposure to pollutants in Sweden. In addition, the wild mink seems to be a suitable
sentinel species that may provide an early warning of alterations in the male reproductive organs related to environmental pollution.
Authors/Creators: | Persson, Sara | ||||||||||
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Title: | The wild male mink as a sentinel for endocrine-disrupting chemicals and reproductive toxicity | ||||||||||
Series Name/Journal: | Acta Universitatis Agriculturae Sueciae | ||||||||||
Year of publishing : | 2013 | ||||||||||
Number: | 2013:65 | ||||||||||
Number of Pages: | 55 | ||||||||||
Papers/manuscripts: |
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Place of Publication: | Uppsala | ||||||||||
Publisher: | Institutionen för kliniska vetenskaper, Sveriges lantbruksuniversitet | ||||||||||
Associated Programs and Other Stakeholders: | SLU - Environmental assessment > Programme Non-Toxic Environment SLU - Research Areas for the Future > Future Animal Health and Welfare (until Jan 2017) | ||||||||||
ISBN for printed version: | 978-91-576-7868-3 | ||||||||||
ISBN for electronic version: | 978-91-576-7869-0 | ||||||||||
ISSN: | 1652-6880 | ||||||||||
Language: | English | ||||||||||
Publication Type: | Doctoral thesis | ||||||||||
Full Text Status: | Public | ||||||||||
Agris subject categories.: | L Animal production > L53 Animal physiology - Reproduction L Animal production > L74 Miscellaneous animal disorders T Pollution > T01 Pollution | ||||||||||
Subjects: | (A) Swedish standard research categories 2011 > 1 Natural sciences > 104 Chemical Sciences > Organic Chemistry (A) Swedish standard research categories 2011 > 4 Agricultural Sciences > 403 Veterinary Science > Pathobiology (A) Swedish standard research categories 2011 > 4 Agricultural Sciences > 403 Veterinary Science > Clinical Science (A) Swedish standard research categories 2011 > 4 Agricultural Sciences > 405 Other Agricultural Sciences > Environmental Sciences related to Agriculture and Land-use | ||||||||||
Agrovoc terms: | minks, males, wild animals, indicator animals, reproductive disorders, endocrine glands, pollutants, toxic substances, chemical compounds, polychlorinated biphenyls, organobromine compounds, dde | ||||||||||
Keywords: | mink, endocrine-disrupting chemicals, male reproduction, PCB, PBDE, perfluoroalkyl acids, PFOS, DDE, anogenital distance, penis, baculum | ||||||||||
URN:NBN: | urn:nbn:se:slu:epsilon-e-1643 | ||||||||||
Permanent URL: | http://urn.kb.se/resolve?urn=urn:nbn:se:slu:epsilon-e-1643 | ||||||||||
ID Code: | 10814 | ||||||||||
Faculty: | VH - Faculty of Veterinary Medicine and Animal Science | ||||||||||
Department: | (VH) > Dept. of Clinical Sciences | ||||||||||
Deposited By: | Sara Persson | ||||||||||
Deposited On: | 25 Sep 2013 13:25 | ||||||||||
Metadata Last Modified: | 14 Dec 2014 13:11 |
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