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Defocused CO2 laser irradiation in the rehabilitation of horses

an experimental and clinical study

Bergh, Anna (2006). Defocused CO2 laser irradiation in the rehabilitation of horses. Diss. (sammanfattning/summary) Uppsala : Sveriges lantbruksuniv., Acta Universitatis agriculturae Sueciae, 1652-6880 ; 2006:54
ISBN 91-576-7103-6
[Doctoral thesis]

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Abstract

There is an increasing interest in the use of physical medicine in rehabilitation of animals. The main goal in rehabilitation is to regain best possible physical function after illness or injury, by use of different physical modalities. The aim of the present investigation was to study the photothermal effects of defocused CO2 laser irradiation on equine tissue, one modality used in the rehabilitation of horses. The thesis comprises studies on the effect of irradiation on temperature, blood flow, morphology, concentration of anti-inflammatory and pain modulating mediators, and finally, lameness due to traumatic arthritis of the fetlock joint. Three experimental studies revealed that defocused CO2 irradiation (91 J/cm2) causes a moderate to vigorous heating effect (3-6 ˚C) in superficial tissues, with a concomitant increase in blood flow, detected by Laser Doppler Flowmetry. Mild to severe dose-dependent morphological changes were detected in the skin after irradiation with doses ranging from therapeutic to near-surgical (91-450 J/cm2). A clinical study demonstrated a decrease in the degree of lameness in both groups of lame horses after irradiation. No statistical difference was detected between lame horses treated with laser or placebo, evaluated by conventional lameness examination and accelerometer technique. Nor was there a difference in the concentration of inflammatory mediators such as substance P and PGE2, or the endogeneous opioid Met-enkephalin-Arg-Phe in synovia. A higher concentration of Met-enkephalin-Arg-Phe was measured in sound horses compared to horses with traumatic arthritis. In conclusion, the present thesis reveals that irradiation with defocused CO2 laser causes a moderate to vigorous heating effect in superficial tissue, and a marked increase in blood flow. The increase in temperature was of such intensity that there is a potential risk of thermal injuries to the skin. The results also suggest that treatment with defocused CO2 laser is not statistically better than placebo at reducing the grade of lameness in horse with traumatic arthritis of the fetlock joint.

Authors/Creators:Bergh, Anna
Title:Defocused CO2 laser irradiation in the rehabilitation of horses
Subtitle:an experimental and clinical study
Year of publishing :2006
Volume:2006:54
Number of Pages:49
Papers/manuscripts:
NumberReferences
ALLPapers I-V The present thesis is based on the following papers, which will be referred to by their Roman numerals: I: Anna Bergh, Görel Nyman, Thomas Lundeberg and Stig Drevemo. 2005. Effect of defocused CO2 laser on equine skin, subcutis and fetlock joint temperature. Equine and Comparative Exercise Physiology 2(1):61-69. II: Anna Bergh, Görel Nyman, Thomas Lundeberg and Stig Drevemo. 2006. Effect of defocused CO2 laser on equine tissue perfusion. Acta Veterinaria Scandinavia 47(1):33-42. III: Anna Bergh, Yvonne Ridderstråle and Stina Ekman. Defocused CO2 laser on equine skin: A light microscopy study. (Manuscript). IV: Anna Bergh, Görel Nyman, Mattias Hallberg, Qin Zhou, Lars Roepstorff, Stig Drevemo and Karin Roethlisberger-Holm. Defocused CO2 laser therapy in traumatic arthritis of the fetlock joint: A randomised clinical study. (Manuscript).
Place of Publication:Uppsala
ISBN for printed version:91-576-7103-6
ISSN:1652-6880
Language:English
Publication Type:Doctoral thesis
Full Text Status:Public
Agrovoc terms:horses, therapy, laser radiation, histopathology, arthritis, lesions, clinical trials
Keywords:rehabilitation, laser therapy, horses, thermal effect, Laser Doppler Flowmetry, histopathology, Met-enkephalin-Arg-Phe, traumatic arthritis, accelerometer technique
URN:NBN:urn:nbn:se:slu:epsilon-1147
Permanent URL:
http://urn.kb.se/resolve?urn=urn:nbn:se:slu:epsilon-1147
ID Code:1167
Department:(VH) > Dept. of Anatomy, Physiology and Biochemistry
Deposited By: Anna Bergh
Deposited On:17 Aug 2006 00:00
Metadata Last Modified:02 Dec 2014 10:10

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