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Neuropeptides in the Antennal Lobe of the Yellow Fever Mosquito, Aedes aegypti.

Purayil, Siju and Reifenrath, Anna and Scheiblich, Hannah and Neupert, Susanne and Predel, Reinhard and Hansson, Bill and Schachtner, Joachim and Ignell, Rickard (2014). Neuropeptides in the Antennal Lobe of the Yellow Fever Mosquito, Aedes aegypti. Journal of comparative neurology. 522:3, 592-608
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Abstract

For many insects, including mosquitoes, olfaction is the dominant modality regulating their behavioral repertoire. Many neurochemicals modulate olfactory information in the central nervous system, including the primary olfactory center of insects, the antennal lobe. The most diverse and versatile neurochemicals in the insect nervous system are found in the neuropeptides. In the present study, we analyzed neuropeptides in the antennal lobe of the yellow fever mosquito, Aedes aegypti, a major vector of arboviral diseases. Direct tissue profiling of the antennal lobe by matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) mass spectrometry indicated the presence of 28 mature products from 10 different neuropeptide genes. In addition, immunocytochemical techniques were used to describe the cellular location of the products of up to seven of these genes within the antennal lobe. Allatostatin A, allatotropin, SIFamide, FMRFamide-related peptides, short neuropeptide F, myoinhibitory peptide, and tachykinin-related peptides were found to be expressed in local interneurons and extrinsic neurons of the antennal lobe. Building on these results, we discuss the possible role of neuropeptide signaling in the antennal lobe of Ae. aegypti. J. Comp. Neurol. 522:592-608, 2014. (c) 2013 Wiley Periodicals, Inc.

Authors/Creators:Purayil, Siju and Reifenrath, Anna and Scheiblich, Hannah and Neupert, Susanne and Predel, Reinhard and Hansson, Bill and Schachtner, Joachim and Ignell, Rickard
Title:Neuropeptides in the Antennal Lobe of the Yellow Fever Mosquito, Aedes aegypti.
Series/Journal:Journal of comparative neurology (1096-9861)
Year of publishing :2014
Volume:522
Number:3
Page range:592-608
Number of Pages:17
Publisher:Wiley Periodicals Inc.
ISSN:1096-9861
Language:English
Publication Type:Journal article
Refereed:Yes
Article category:Scientific peer reviewed
Version:Published version
Full Text Status:Public
Subjects:(A) Swedish standard research categories 2011 > 1 Natural sciences > 106 Biological Sciences (Medical to be 3 and Agricultural to be 4) > Structural Biology
(A) Swedish standard research categories 2011 > 1 Natural sciences > 106 Biological Sciences (Medical to be 3 and Agricultural to be 4) > Cell Biology
(A) Swedish standard research categories 2011 > 1 Natural sciences > 106 Biological Sciences (Medical to be 3 and Agricultural to be 4) > Zoology
(A) Swedish standard research categories 2011 > 1 Natural sciences > 106 Biological Sciences (Medical to be 3 and Agricultural to be 4) > Other Biological Topics
Keywords:olfaction, neuromodulation, mass spectrometry, immunocytochemistry, insect brain
URN:NBN:urn:nbn:se:slu:epsilon-e-2976
Permanent URL:
http://urn.kb.se/resolve?urn=urn:nbn:se:slu:epsilon-e-2976
Additional ID:
Type of IDID
Web of Science (WoS)000328656300006
DOI10.1002/cne.23434
ID Code:11769
Faculty:LTV - Fakulteten för landskapsarkitektur, trädgårds- och växtproduktionsvetenskap
Department:(LTJ, LTV) > Department of Plant Protection Biology
External funders:FORMAS and Swedish Research Council
Deposited By: SLUpub Connector
Deposited On:06 Oct 2015 11:09
Metadata Last Modified:15 Dec 2015 05:08

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