Home About Browse Search
Svenska


Antimicrobial resistant Escherichia coli in faeces from preweaned dairy calves

prevalence, risk factors, and spread

Duse, Anna (2015). Antimicrobial resistant Escherichia coli in faeces from preweaned dairy calves. Diss. (sammanfattning/summary) Uppsala : Sveriges lantbruksuniv., Acta Universitatis agriculturae Sueciae, 1652-6880 ; 2015:47
ISBN 978-91-576-8292-5
eISBN 978-91-576-8293-2
[Doctoral thesis]

[img]
Preview
PDF
517kB

Abstract

Antimicrobial resistant (AMR) bacteria are increasing threats for human and veterinary medicine. Faecal Escherichia coli (E. coli) from preweaned dairy calves is often resistant to multiple antimicrobials and calves may therefore serve as reservoirs for these bacteria and their resistance genes. This thesis investigated the prevalence, risk factors, and spread of resistant E. coli on Swedish dairy farms, with special emphasis on quinolone resistant E. coli (QREC). Faecal samples from preweaned calves and post-partum cows were analysed for resistant E. coli and set in relation to potential risk
factors. The farm environment was sampled to study the occurrence and spread of QREC.

The occurrence of faecal resistant E. coli in calves was strongly age-dependent, but was also associated with herd size, milking system, calf housing, and geographic location of the farm. Treatment with some broad-spectrum antimicrobials in cows or calves increased the occurrence of resistant E. coli in calves. Feeding waste milk (WM) from cows treated with antimicrobials during lactation to calves increased the proportion of streptomycin and quinolone resistant E. coli in calves, but feeding waste colostrum from cows treated with antimicrobials at drying off had no effect on AMR E. coli. Feeding such colostrum or milk to calves was a common practice on Swedish dairy
farms, in particular on farms in southern Sweden, on non-organic farms, and on farms with tie stall housing. On farms where QREC is common in faeces of calves, these
bacteria were also widespread in the farm environment. In particular, the calf feed andwater trough contained QREC. The same QREC genotype was found throughout the
same and on different farms, suggesting contagious spread of QREC within and between farms. Fluoroquinolone treatment, WM feeding, group calving, poor farm
hygiene, purchasing cattle or shared animal transports were some risk factors for increasing the occurrence of QREC on the farm.

Altogether, the results indicate that proper biosecurity and improved hygiene, less exposure to broad-spectrum antimicrobials, and restrictive waste milk feeding may be
important factors to reduce the burden of AMR E. coli on dairy farms.

Authors/Creators:Duse, Anna
Title:Antimicrobial resistant Escherichia coli in faeces from preweaned dairy calves
Subtitle:prevalence, risk factors, and spread
Series/Journal:Acta Universitatis agriculturae Sueciae (1652-6880)
Year of publishing :28 April 2015
Depositing date:28 April 2015
Volume:2015:47
Number of Pages:95
Papers/manuscripts:
NumberReferences
IDuse A., Waller K.P., Emanuelson U., Unnerstad H.E., Persson Y., Bengtsson B. (2013). Farming practices in Sweden related to feeding milk and colostrum from cows treated with antimicrobials to dairy calves. Acta Veterinaria Scandinavica 55, 49.
IIDuse A., Waller K.P., Emanuelson U., Unnerstad H.E., Persson Y., Bengtsson B. (2015). Risk factors for antimicrobial resistance in fecal Escherichia coli from preweaned dairy calves. Journal of Dairy Science 98(1), 500–516.
IIIDuse A., Waller K.P., Emanuelson U., Unnerstad H.E., Persson Y., Bengtsson B. Risk factors for quinolone resistant Escherichia coli in faeces from preweaned dairy calves and post-partum dairy cows. (Submitted manuscript).
IVDuse A., Waller K.P., Emanuelson U., Unnerstad H.E., Persson Y., Bengtsson B. Occurrence and spread of quinolone resistant Escherichia coli on Swedish dairy farms (Manuscript).
Place of Publication:Uppsala
Publisher:Department of Clinical Sciences, Swedish University of Agricultural Sciences
ISBN for printed version:978-91-576-8292-5
ISBN for electronic version:978-91-576-8293-2
ISSN:1652-6880
Language:English
Publication Type:Doctoral thesis
Full Text Status:Public
Agris subject categories.:L Animal production > L73 Animal diseases
Subjects:(A) Swedish standard research categories 2011 > 3 Medical and Health Sciences > 303 Health Sciences > Public Health, Global Health, Social Medicine and Epidemiology
(A) Swedish standard research categories 2011 > 4 Agricultural Sciences > 403 Veterinary Science > Clinical Science
Agrovoc terms:calves, escherichia coli, resistance to antibiotics, antimicrobials, genetic variation, milk, colostrum, risk factors, dairy farms, sweden
Keywords:Calf, Escherichia coli, Antimicrobial resistance, Waste milk, Antimicrobials, Quinolone resistance, Genetic diversity, Risk factor, Spread
URN:NBN:urn:nbn:se:slu:epsilon-e-2600
Permanent URL:
http://urn.kb.se/resolve?urn=urn:nbn:se:slu:epsilon-e-2600
ID Code:12152
Faculty:VH - Faculty of Veterinary Medicine and Animal Science
Department:(VH) > Dept. of Clinical Sciences
External funders:Stiftelsen Lantbruksforskning
Deposited By: Anna Duse
Deposited On:29 Apr 2015 04:20
Metadata Last Modified:13 May 2015 12:22

Repository Staff Only: item control page

Downloads

Downloads per year (since September 2012)

View more statistics

Downloads
Hits