prevalence, risk factors, and spread
Duse, Anna
(2015).
Antimicrobial resistant Escherichia coli in faeces from preweaned dairy calves.
Diss. (sammanfattning/summary)
Uppsala :
Sveriges lantbruksuniv.,
Acta Universitatis Agriculturae Sueciae, 1652-6880
; 2015:47
ISBN 978-91-576-8292-5
eISBN 978-91-576-8293-2
[Doctoral thesis]
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PDF
517kB |
Abstract
Antimicrobial resistant (AMR) bacteria are increasing threats for human and veterinary medicine. Faecal Escherichia coli (E. coli) from preweaned dairy calves is often resistant to multiple antimicrobials and calves may therefore serve as reservoirs for these bacteria and their resistance genes. This thesis investigated the prevalence, risk factors, and spread of resistant E. coli on Swedish dairy farms, with special emphasis on quinolone resistant E. coli (QREC). Faecal samples from preweaned calves and post-partum cows were analysed for resistant E. coli and set in relation to potential risk
factors. The farm environment was sampled to study the occurrence and spread of QREC.
The occurrence of faecal resistant E. coli in calves was strongly age-dependent, but was also associated with herd size, milking system, calf housing, and geographic location of the farm. Treatment with some broad-spectrum antimicrobials in cows or calves increased the occurrence of resistant E. coli in calves. Feeding waste milk (WM) from cows treated with antimicrobials during lactation to calves increased the proportion of streptomycin and quinolone resistant E. coli in calves, but feeding waste colostrum from cows treated with antimicrobials at drying off had no effect on AMR E. coli. Feeding such colostrum or milk to calves was a common practice on Swedish dairy
farms, in particular on farms in southern Sweden, on non-organic farms, and on farms with tie stall housing. On farms where QREC is common in faeces of calves, these
bacteria were also widespread in the farm environment. In particular, the calf feed andwater trough contained QREC. The same QREC genotype was found throughout the
same and on different farms, suggesting contagious spread of QREC within and between farms. Fluoroquinolone treatment, WM feeding, group calving, poor farm
hygiene, purchasing cattle or shared animal transports were some risk factors for increasing the occurrence of QREC on the farm.
Altogether, the results indicate that proper biosecurity and improved hygiene, less exposure to broad-spectrum antimicrobials, and restrictive waste milk feeding may be
important factors to reduce the burden of AMR E. coli on dairy farms.
Authors/Creators: | Duse, Anna | ||||||||||
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Title: | Antimicrobial resistant Escherichia coli in faeces from preweaned dairy calves | ||||||||||
Subtitle: | prevalence, risk factors, and spread | ||||||||||
Series/Journal: | Acta Universitatis Agriculturae Sueciae (1652-6880) | ||||||||||
Year of publishing : | 28 April 2015 | ||||||||||
Depositing date: | 28 April 2015 | ||||||||||
Number: | 2015:47 | ||||||||||
Number of Pages: | 95 | ||||||||||
Papers/manuscripts: |
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Place of Publication: | Uppsala | ||||||||||
Publisher: | Department of Clinical Sciences, Swedish University of Agricultural Sciences | ||||||||||
ISBN for printed version: | 978-91-576-8292-5 | ||||||||||
ISBN for electronic version: | 978-91-576-8293-2 | ||||||||||
ISSN: | 1652-6880 | ||||||||||
Language: | English | ||||||||||
Publication Type: | Doctoral thesis | ||||||||||
Full Text Status: | Public | ||||||||||
Agris subject categories.: | L Animal production > L73 Animal diseases | ||||||||||
Subjects: | (A) Swedish standard research categories 2011 > 3 Medical and Health Sciences > 303 Health Sciences > Public Health, Global Health, Social Medicine and Epidemiology (A) Swedish standard research categories 2011 > 4 Agricultural Sciences > 403 Veterinary Science > Clinical Science | ||||||||||
Agrovoc terms: | calves, escherichia coli, resistance to antibiotics, antimicrobials, genetic variation, milk, colostrum, risk factors, dairy farms, sweden | ||||||||||
Keywords: | Calf, Escherichia coli, Antimicrobial resistance, Waste milk, Antimicrobials, Quinolone resistance, Genetic diversity, Risk factor, Spread | ||||||||||
URN:NBN: | urn:nbn:se:slu:epsilon-e-2600 | ||||||||||
Permanent URL: | http://urn.kb.se/resolve?urn=urn:nbn:se:slu:epsilon-e-2600 | ||||||||||
ID Code: | 12152 | ||||||||||
Faculty: | VH - Faculty of Veterinary Medicine and Animal Science | ||||||||||
Department: | (VH) > Dept. of Clinical Sciences | ||||||||||
External funders: | Stiftelsen Lantbruksforskning | ||||||||||
Deposited By: | Anna Duse | ||||||||||
Deposited On: | 29 Apr 2015 04:20 | ||||||||||
Metadata Last Modified: | 10 Sep 2020 13:41 |
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