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Feeding regulates sex pheromone attraction and courtship in Drosophila females

Lebreton, Sebastien and Borrero, Felipe and Trona, Federica and Bilz, Florian and Grabe, Veit and Becher, Paul G and Carlsson, Mikael A. and Nässel, Dick and Hansson, Bill and Sachse, Silke and Witzgall, Peter (2015). Feeding regulates sex pheromone attraction and courtship in Drosophila females. Scientific Reports. 5, 1-11
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Official URL: http://www.nature.com/articles/srep13132

Abstract

In Drosophila melanogaster, gender-specific behavioural responses to the male-produced sex pheromone cis-vaccenyl acetate (cVA) rely on sexually dimorphic, third-order neural circuits. We show that nutritional state in female flies modulates cVA perception in first-order olfactory neurons. Starvation increases, and feeding reduces attraction to food odour, in both sexes. Adding cVA to food odour, however, maintains attraction in fed females, while it has no effect in males. Upregulation of sensitivity and behavioural responsiveness to cVA in fed females is paralleled by a strong increase in receptivity to male courtship. Functional imaging of the antennal lobe (AL), the olfactory centre in the insect brain, shows that olfactory input to DA1 and VM2 glomeruli is also modulated by starvation. Knocking down insulin receptors in neurons converging onto the DA1 glomerulus suggests that insulin-signalling partly controls pheromone perception in the AL, and adjusts cVA attraction according to nutritional state and sexual receptivity in Drosophila females.

Authors/Creators:Lebreton, Sebastien and Borrero, Felipe and Trona, Federica and Bilz, Florian and Grabe, Veit and Becher, Paul G and Carlsson, Mikael A. and Nässel, Dick and Hansson, Bill and Sachse, Silke and Witzgall, Peter
Title:Feeding regulates sex pheromone attraction and courtship in Drosophila females
Series/Journal:Scientific Reports (2045-2322)
Year of publishing :2015
Volume:5
Page range:1-11
Number of Pages:11
Publisher:Nature Publishing Group
ISSN:2045-2322
Language:English
Publication Type:Journal article
Refereed:Yes
Article category:Scientific peer reviewed
Version:Published version
Full Text Status:Public
Subjects:(A) Swedish standard research categories 2011 > 1 Natural sciences > 106 Biological Sciences (Medical to be 3 and Agricultural to be 4) > Behavioural Sciences Biology
(A) Swedish standard research categories 2011 > 1 Natural sciences > 106 Biological Sciences (Medical to be 3 and Agricultural to be 4) > Zoology
(A) Swedish standard research categories 2011 > 1 Natural sciences > 106 Biological Sciences (Medical to be 3 and Agricultural to be 4) > Ecology
Keywords:Olfactory neurons, Antennal lobes, Odor preference, Melanogaster
URN:NBN:urn:nbn:se:slu:epsilon-e-2904
Permanent URL:
http://urn.kb.se/resolve?urn=urn:nbn:se:slu:epsilon-e-2904
Additional ID:
Type of IDID
Web of Science (WoS)000359196200001
DOI10.1038/srep13132
ID Code:12565
Faculty:LTV - Fakulteten för landskapsarkitektur, trädgårds- och växtproduktionsvetenskap
Department:(LTJ, LTV) > Department of Plant Protection Biology
External funders:FORMAS
Deposited By: SLUpub Connector
Deposited On:04 Sep 2015 08:43
Metadata Last Modified:07 Feb 2016 03:26

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