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Isolation and Molecular Characterization of Brucella Isolates in Cattle Milk in Uganda

Rwabiita Mugizi, Denis and Muradrasoli, Shaman and Boqvist, Sofia and Erume, Joseph and Nasinyama, George and Waiswa, Charles and Mboowa, Gerald and Klint, Markus and Magnusson, Ulf (2015). Isolation and Molecular Characterization of Brucella Isolates in Cattle Milk in Uganda. BioMed Research International. 2015, 1-9
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Abstract

Brucellosis is endemic in livestock and humans in Uganda and its transmission involves amultitude of risk factors like consumption of milk from infected cattle. To shed new light on the epidemiology of brucellosis in Uganda the present study used phenotypic and molecular approaches to delineate the Brucella species, biovars, and genotypes shed in cattle milk. Brucella abortus without a biovar designation was isolated from eleven out of 207 milk samples from cattle in Uganda. These isolates had a genomic monomorphism at 16 variable number tandem repeat (VNTR) loci and showed in turn high levels of genetic variation when compared with other African strains or other B. abortus biovars from other parts of the world. This study further highlights the usefulness of MLVA as an epidemiological tool for investigation of Brucella infections.

Authors/Creators:Rwabiita Mugizi, Denis and Muradrasoli, Shaman and Boqvist, Sofia and Erume, Joseph and Nasinyama, George and Waiswa, Charles and Mboowa, Gerald and Klint, Markus and Magnusson, Ulf
Title:Isolation and Molecular Characterization of Brucella Isolates in Cattle Milk in Uganda
Series/Journal:BioMed Research International (2314-6141)
Year of publishing :2015
Volume:2015
Page range:1-9
Number of Pages:9
Publisher:Hindawi
ISSN:2314-6141
Language:English
Additional Information:Article ID 720413
Publication Type:Journal article
Refereed:Yes
Article category:Scientific peer reviewed
Version:Published version
Full Text Status:Public
Subjects:(A) Swedish standard research categories 2011 > 3 Medical and Health Sciences > 303 Health Sciences > Public Health, Global Health, Social Medicine and Epidemiology
(A) Swedish standard research categories 2011 > 4 Agricultural Sciences > 403 Veterinary Science > Medical Bioscience
Keywords:epidemiology, brucellosis, Brucella, milk, cattle
URN:NBN:urn:nbn:se:slu:epsilon-e-3267
Permanent URL:
http://urn.kb.se/resolve?urn=urn:nbn:se:slu:epsilon-e-3267
Additional ID:
Type of IDID
Web of Science (WoS)000351107500001
DOI10.1155/2015/720413
ID Code:13102
Faculty:VH - Faculty of Veterinary Medicine and Animal Science
Department:(VH) > Dept. of Clinical Sciences
(VH) > Dept. of Biomedical Sciences and Veterinary Public Health
Deposited By: SLUpub Connector
Deposited On:29 Feb 2016 12:42
Metadata Last Modified:06 Mar 2016 14:34

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