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Widespread episodic thiamine deficiency in Northern Hemisphere wildlife

Balk, Lennart and Karlsson, Simon and Strömquist, Jennie and Börjeson, Hans and Hansson, Tomas (2016). Widespread episodic thiamine deficiency in Northern Hemisphere wildlife. Scientific Reports. 6, 1-13
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Abstract

Many wildlife populations are declining at rates higher than can be explained by known threats to biodiversity. Recently, thiamine (vitamin B-1) deficiency has emerged as a possible contributing cause. Here, thiamine status was systematically investigated in three animal classes: bivalves, ray-finned fishes, and birds. Thiamine diphosphate is required as a cofactor in at least five life-sustaining enzymes that are required for basic cellular metabolism. Analysis of different phosphorylated forms of thiamine, as well as of activities and amount of holoenzyme and apoenzyme forms of thiaminedependent enzymes, revealed episodically occurring thiamine deficiency in all three animal classes. These biochemical effects were also linked to secondary effects on growth, condition, liver size, blood chemistry and composition, histopathology, swimming behaviour and endurance, parasite infestation, and reproduction. It is unlikely that the thiamine deficiency is caused by impaired phosphorylation within the cells. Rather, the results point towards insufficient amounts of thiamine in the food. By investigating a large geographic area, by extending the focus from lethal to sublethal thiamine deficiency, and by linking biochemical alterations to secondary effects, we demonstrate that the problem of thiamine deficiency is considerably more widespread and severe than previously reported.

Authors/Creators:Balk, Lennart and Karlsson, Simon and Strömquist, Jennie and Börjeson, Hans and Hansson, Tomas
Title:Widespread episodic thiamine deficiency in Northern Hemisphere wildlife
Series/Journal:Scientific Reports (2045-2322)
Year of publishing :2016
Volume:6
Page range:1-13
Number of Pages:13
Publisher:Macmillan Publishers Limited, part of Springer Nature.
Associated Programs and Other Stakeholders:SLU - Environmental assessment > Programme Coastal and sea areas
SLU - Environmental assessment > Programme Lakes and watercourses
ISSN:2045-2322
Language:English
Publication Type:Journal article
Refereed:Yes
Article category:Scientific peer reviewed
Version:Published version
Full Text Status:Public
Subjects:(A) Swedish standard research categories 2011 > 1 Natural sciences > 106 Biological Sciences (Medical to be 3 and Agricultural to be 4) > Zoology
(A) Swedish standard research categories 2011 > 1 Natural sciences > 105 Earth and Related Environmental Sciences > Environmental Sciences (social aspects to be 507)
(A) Swedish standard research categories 2011 > 1 Natural sciences > 106 Biological Sciences (Medical to be 3 and Agricultural to be 4) > Biochemistry and Molecular Biology
Agrovoc terms:deficiency diseases, nature conservation, thiamin
Keywords:Thiamine, Anguilla, eel, salmon, herring, eider, Mytilus
URN:NBN:urn:nbn:se:slu:epsilon-e-4084
Permanent URL:
http://urn.kb.se/resolve?urn=urn:nbn:se:slu:epsilon-e-4084
Additional ID:
Type of IDID
Web of Science (WoS)000389688300001
DOI10.1038/srep38821
ID Code:14214
Faculty:NJ - Fakulteten för naturresurser och jordbruksvetenskap
Department:(NL, NJ) > Department of Aquatic Resources
Deposited By: SLUpub Connector
Deposited On:06 Apr 2017 08:59
Metadata Last Modified:06 Apr 2017 08:59

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