Lindgren, Per-Erik and Alm Bergvall, Ulrika and Lundkvist, Åke and Kjellander, Petter and Wille, Michelle and Borg, O. and Chirico, J.
(2017).
Expansion of spatial and host range of Puumala virus in Sweden: an increasing threat for humans?
Epidemiology and infection. 145
, 1642-1648
[Research article]
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Abstract
Hantaviruses are globally distributed and cause severe human disease. Puumala hantavirus (PUUV) is the most common species in Northern Europe, and the only hantavirus confirmed to circulate in Sweden, restricted to the northern regions of the country. In this study, we aimed to further add to the natural ecology of PUUV in Sweden by investigating prevalence, and spatial and host species infection patterns. Specifically, we wanted to ascertain whether PUUV was present in the natural reservoir, the bank vole (Myodes glareolus) further south than Dalalven river, in south-central Sweden, and whether PUUV can be detected in other rodent species in addition to the natural reservoir. In total, 559 animals were collected at Grimso (59 degrees 43 ' N; 15 degrees 28 ' E), Sala (59 degrees 55 ' N; 16 degrees 36 ' E) and Bogesund (59 degrees 24 ' N; 18 degrees 14 ' E) in south-central Sweden between May 2013 and November 2014. PUUV ELISA-reactive antibodies were found both in 2013 (22/295) and in 2014 (18/264), and nine samples were confirmed as PUUV-specific by focus reduction neutralization test. Most of the PUUV-specific samples were from the natural host, the bank vole, but also from other rodent hosts, indicating viral spill-over. Finally, we showed that PUUV is present in more highly populated central Sweden.
| Authors/Creators: | Lindgren, Per-Erik and Alm Bergvall, Ulrika and Lundkvist, Åke and Kjellander, Petter and Wille, Michelle and Borg, O. and Chirico, J. | ||||||
|---|---|---|---|---|---|---|---|
| Title: | Expansion of spatial and host range of Puumala virus in Sweden: an increasing threat for humans? | ||||||
| Series Name/Journal: | Epidemiology and infection | ||||||
| Year of publishing : | 2017 | ||||||
| Volume: | 145 | ||||||
| Page range: | 1642-1648 | ||||||
| Number of Pages: | 7 | ||||||
| Publisher: | Cambridge University Press | ||||||
| ISSN: | 1469-4409 | ||||||
| Language: | English | ||||||
| Publication Type: | Research article | ||||||
| Refereed: | Yes | ||||||
| Article category: | Scientific peer reviewed | ||||||
| Version: | Accepted version | ||||||
| Full Text Status: | Public | ||||||
| Subjects: | (A) Swedish standard research categories 2011 > 1 Natural sciences > 106 Biological Sciences (Medical to be 3 and Agricultural to be 4) > Ecology (A) Swedish standard research categories 2011 > 3 Medical and Health Sciences > 303 Health Sciences > Public Health, Global Health, Social Medicine and Epidemiology | ||||||
| Agrovoc terms: | zoonoses, voles, hantavirus | ||||||
| Keywords: | Bank vole, Bunyaviridae, disease emergence, hantavirus, Myodes glareolus, Puumala virus, Sweden, zoonosis | ||||||
| URN:NBN: | urn:nbn:se:slu:epsilon-e-4437 | ||||||
| Permanent URL: | http://urn.kb.se/resolve?urn=urn:nbn:se:slu:epsilon-e-4437 | ||||||
| Additional ID: |
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| ID Code: | 14626 | ||||||
| Faculty: | NJ - Fakulteten för naturresurser och jordbruksvetenskap | ||||||
| Department: | (NL, NJ) > Dept. of Ecology (S) > Dept. of Ecology | ||||||
| Deposited By: | SLUpub Connector | ||||||
| Deposited On: | 27 Oct 2017 09:17 | ||||||
| Metadata Last Modified: | 30 Oct 2017 21:57 |
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