Thaduri, Srinivas and Stephan, Jörg and Rodrigues De Miranda, Joachim and Locke, Barbara
(2019).
Disentangling host-parasite-pathogen interactions in a varroa-resistant honeybee population reveals virus tolerance as an independent, naturally adapted survival mechanism.
Scientific Reports. 9
, 1-10
[Research article]
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Available under License Creative Commons Attribution. 1MB |
Official URL: https://doi.org/10.1038/s41598-019-42741-6
Abstract
The ectoparasitic mite, Varroa destructor, is unarguably the leading cause of honeybee (Apis mellifera) mortality worldwide through its role as a vector for lethal viruses, in particular, strains of the Deformed wing virus (DWV) and Acute bee paralysis virus (ABPV) complexes. This multi-level system of hostparasite-pathogen interactions makes it difcult to investigate efects of either the mite or the virus on natural host survival. The aim of this study was to remove confounding efects of varroa to examine the role of virus susceptibility in the enhanced survival of a naturally adapted Swedish mite-resistant (MR) honeybee population, relative to mite-susceptible (MS) honeybees. Caged adult bees and laboratory reared larvae, from varroa-free colonies, were inoculated with DWV and ABPV in a series of feeding infection experiments, while control groups received virus-free food. Virus infections were monitored using RT-qPCR assays in individuals sampled over a time course. In both adults and larvae the DWV and ABPV infection dynamics were nearly identical between MR and MS groups, but MS adults sufered signifcantly higher mortality than MR adults. Results suggest virus tolerance, rather than reduced susceptibility or virus resistance, is an important component of the natural survival of this honeybee population.
Authors/Creators: | Thaduri, Srinivas and Stephan, Jörg and Rodrigues De Miranda, Joachim and Locke, Barbara | ||||
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Title: | Disentangling host-parasite-pathogen interactions in a varroa-resistant honeybee population reveals virus tolerance as an independent, naturally adapted survival mechanism | ||||
Series Name/Journal: | Scientific Reports | ||||
Year of publishing : | 2019 | ||||
Volume: | 9 | ||||
Page range: | 1-10 | ||||
Number of Pages: | 10 | ||||
Publisher: | NatureResearch | ||||
ISSN: | 2045-2322 | ||||
Language: | English | ||||
Publication Type: | Research article | ||||
Refereed: | Yes | ||||
Article category: | Scientific peer reviewed | ||||
Version: | Published version | ||||
Copyright: | Creative Commons: Attribution 4.0 | ||||
Full Text Status: | Public | ||||
Subjects: | (A) Swedish standard research categories 2011 > 1 Natural sciences > 106 Biological Sciences (Medical to be 3 and Agricultural to be 4) > Ecology | ||||
Keywords: | honeybees, Apis mellifera, parasites, ectoparasitic mites, Varroa destructor, mite-resistance, virus resistance, RT-qPCR assays | ||||
URN:NBN: | urn:nbn:se:slu:epsilon-p-99881 | ||||
Permanent URL: | http://urn.kb.se/resolve?urn=urn:nbn:se:slu:epsilon-p-99881 | ||||
Additional ID: |
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ID Code: | 16114 | ||||
Faculty: | NJ - Fakulteten för naturresurser och jordbruksvetenskap | ||||
Department: | (NL, NJ) > Dept. of Ecology (S) > Dept. of Ecology | ||||
Deposited By: | SLUpub Connector | ||||
Deposited On: | 21 May 2019 10:58 | ||||
Metadata Last Modified: | 21 May 2019 10:58 |
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