Han, Biao and Baruah, Kartik and Cox, Eric and Vanrompay, Daisy and Bossier, Peter
(2020).
Structure-Functional Activity Relationship of beta-Glucans From the Perspective of Immunomodulation: A Mini-Review.
Frontiers in Immunology. 11
, 658
, 1-8
[Article Review/Survey]
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Abstract
beta-Glucans are a heterogeneous group of glucose polymers with a common structure comprising a main chain of beta-(1,3) and/or beta-(1,4)-glucopyranosyl units, along with side chains with various branches and lengths. beta-Glucans initiate immune responses via immune cells, which become activated by the binding of the polymer to specific receptors. However, beta-glucans from different sources also differ in their structure, conformation, physical properties, binding affinity to receptors, and thus biological functions. The mechanisms behind this are not fully understood. This mini-review provides a comprehensive and up-to-date commentary on the relationship between beta-glucans' structure and function in relation to their use for immunomodulation.
| Authors/Creators: | Han, Biao and Baruah, Kartik and Cox, Eric and Vanrompay, Daisy and Bossier, Peter | ||||||
|---|---|---|---|---|---|---|---|
| Title: | Structure-Functional Activity Relationship of beta-Glucans From the Perspective of Immunomodulation: A Mini-Review | ||||||
| Series Name/Journal: | Frontiers in Immunology | ||||||
| Year of publishing : | 2020 | ||||||
| Volume: | 11 | ||||||
| Article number: | 658 | ||||||
| Number of Pages: | 8 | ||||||
| Publisher: | Frontiers | ||||||
| ISSN: | 1664-3224 | ||||||
| Language: | English | ||||||
| Publication Type: | Article Review/Survey | ||||||
| Article category: | Scientific peer reviewed | ||||||
| Version: | Published version | ||||||
| Copyright: | Creative Commons: Attribution 4.0 | ||||||
| Full Text Status: | Public | ||||||
| Subjects: | (A) Swedish standard research categories 2011 > 4 Agricultural Sciences > 403 Veterinary Science > Pathobiology | ||||||
| Keywords: | beta-glucans, structure-function relationship, immunomodulation, molecular structure, molecular weight, solubility | ||||||
| URN:NBN: | urn:nbn:se:slu:epsilon-p-105999 | ||||||
| Permanent URL: | http://urn.kb.se/resolve?urn=urn:nbn:se:slu:epsilon-p-105999 | ||||||
| Additional ID: |
| ||||||
| ID Code: | 17171 | ||||||
| Faculty: | VH - Faculty of Veterinary Medicine and Animal Science | ||||||
| Department: | (VH) > Dept. of Animal Nutrition and Management | ||||||
| Deposited By: | SLUpub Connector | ||||||
| Deposited On: | 02 Jul 2020 11:05 | ||||||
| Metadata Last Modified: | 15 Jan 2021 19:22 |
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