Cavaleiro Pinto, Marlene and Craveiro, Hélder and Johansson Wensman, Jonas and Carvalheira, Júlio and Berg, Mikael and Thompson, Gertrude
(2019).
Bornaviruses in naturally infected Psittacus erithacus in Portugal: insights of molecular epidemiology and ecology.
Infection Ecology and Epidemiology. 9
, 1682223
, 1-15
[Journal article]
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Abstract
Background: The genus Orthobornavirus comprises non-segmented, negative-stranded RNA viruses able to infect humans, mammals, reptiles and various birds. Parrot bornavirus 1 to 8(PaBV-1 to 8) causes neurological and/or gastrointestinal syndromes and death on psittacines. We aimed to identify and to produce epidemiologic knowledge about the etiologic agent associated with a death of two female Psittacus erithacus(grey parrot).
Methods and Results: Both parrots were submitted for a complete standardised necropsy. Tissue samples were analysed by PCR. The findings in necropsy were compatible with bornavirus infection. Analysis revealed PaBV-4 related with genotypes detected in captive and in wild birds. The N and X proteins of PaBV-4 were more related to avian bornaviruses, while phosphoprotein was more related to variegated squirrel bornavirus 1 (VSBV-1). Within the P gene/phosphoprotein a highly conserved region between and within bornavirus species was found.
Conclusions: Portugal is on the routes of the intensive world trade of psittacines. Broad screening studies are required to help understanding the role of wild birds in the emergence and spread of pathogenic bornaviruses. PaBV-4 phosphoprotein is closer to VSBV-1 associated with lethalencephalitis in humans than with some of the avian bornaviruses. The highly conserved P gene/phosphoprotein region is a good target for molecular diagnostics screenings.
Authors/Creators: | Cavaleiro Pinto, Marlene and Craveiro, Hélder and Johansson Wensman, Jonas and Carvalheira, Júlio and Berg, Mikael and Thompson, Gertrude | ||||
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Title: | Bornaviruses in naturally infected Psittacus erithacus in Portugal: insights of molecular epidemiology and ecology | ||||
Series Name/Journal: | Infection Ecology and Epidemiology | ||||
Year of publishing : | 2019 | ||||
Volume: | 9 | ||||
Article number: | 1682223 | ||||
Number of Pages: | 8 | ||||
Publisher: | Taylor & Francis | ||||
ISSN: | 2000-8686 | ||||
Language: | English | ||||
Publication Type: | Journal article | ||||
Article category: | Scientific peer reviewed | ||||
Version: | Published version | ||||
Copyright: | Creative Commons: Attribution-Noncommercial 4.0 | ||||
Full Text Status: | Public | ||||
Subjects: | (A) Swedish standard research categories 2011 > 4 Agricultural Sciences > 403 Veterinary Science > Pathobiology (A) Swedish standard research categories 2011 > 4 Agricultural Sciences > 403 Veterinary Science > Clinical Science | ||||
Keywords: | Orthobornavirus, RNA viruses | ||||
URN:NBN: | urn:nbn:se:slu:epsilon-p-106452 | ||||
Permanent URL: | http://urn.kb.se/resolve?urn=urn:nbn:se:slu:epsilon-p-106452 | ||||
Additional ID: |
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ID Code: | 17182 | ||||
Faculty: | VH - Faculty of Veterinary Medicine and Animal Science | ||||
Department: | (VH) > Department of Biomedical Science and Veterinary Public Health (VH) > Dept. of Clinical Sciences | ||||
Deposited By: | SLUpub Connector | ||||
Deposited On: | 07 Jul 2020 08:57 | ||||
Metadata Last Modified: | 07 Jul 2020 08:57 |
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