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Bornaviruses in naturally infected Psittacus erithacus in Portugal: insights of molecular epidemiology and ecology

Cavaleiro Pinto, Marlene and Craveiro, Hélder and Johansson Wensman, Jonas and Carvalheira, Júlio and Berg, Mikael and Thompson, Gertrude (2019). Bornaviruses in naturally infected Psittacus erithacus in Portugal: insights of molecular epidemiology and ecology. Infection Ecology and Epidemiology. 9 , 1682223 , 1-15
[Journal article]

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Abstract

Background: The genus Orthobornavirus comprises non-segmented, negative-stranded RNA viruses able to infect humans, mammals, reptiles and various birds. Parrot bornavirus 1 to 8(PaBV-1 to 8) causes neurological and/or gastrointestinal syndromes and death on psittacines. We aimed to identify and to produce epidemiologic knowledge about the etiologic agent associated with a death of two female Psittacus erithacus(grey parrot).
Methods and Results: Both parrots were submitted for a complete standardised necropsy. Tissue samples were analysed by PCR. The findings in necropsy were compatible with bornavirus infection. Analysis revealed PaBV-4 related with genotypes detected in captive and in wild birds. The N and X proteins of PaBV-4 were more related to avian bornaviruses, while phosphoprotein was more related to variegated squirrel bornavirus 1 (VSBV-1). Within the P gene/phosphoprotein a highly conserved region between and within bornavirus species was found.
Conclusions: Portugal is on the routes of the intensive world trade of psittacines. Broad screening studies are required to help understanding the role of wild birds in the emergence and spread of pathogenic bornaviruses. PaBV-4 phosphoprotein is closer to VSBV-1 associated with lethalencephalitis in humans than with some of the avian bornaviruses. The highly conserved P gene/phosphoprotein region is a good target for molecular diagnostics screenings.

Authors/Creators:Cavaleiro Pinto, Marlene and Craveiro, Hélder and Johansson Wensman, Jonas and Carvalheira, Júlio and Berg, Mikael and Thompson, Gertrude
Title:Bornaviruses in naturally infected Psittacus erithacus in Portugal: insights of molecular epidemiology and ecology
Year of publishing :2019
Volume:9
Article number:1682223
Number of Pages:8
Publisher:Taylor & Francis
ISSN:2000-8686
Language:English
Publication Type:Journal article
Article category:Scientific peer reviewed
Version:Published version
Copyright:Creative Commons: Attribution-Noncommercial 4.0
Full Text Status:Public
Subjects:(A) Swedish standard research categories 2011 > 4 Agricultural Sciences > 403 Veterinary Science > Pathobiology
(A) Swedish standard research categories 2011 > 4 Agricultural Sciences > 403 Veterinary Science > Clinical Science
Keywords:Orthobornavirus, RNA viruses
URN:NBN:urn:nbn:se:slu:epsilon-p-106452
Permanent URL:
http://urn.kb.se/resolve?urn=urn:nbn:se:slu:epsilon-p-106452
Additional ID:
Type of IDID
DOI10.1080/20008686.2019.1685632
ID Code:17182
Faculty:VH - Faculty of Veterinary Medicine and Animal Science
Department:(VH) > Department of Biomedical Science and Veterinary Public Health
(VH) > Dept. of Clinical Sciences
Deposited By: SLUpub Connector
Deposited On:07 Jul 2020 08:57
Metadata Last Modified:07 Jul 2020 08:57

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