Home About Browse Search
Svenska


Disease-related and overall survival in dogs with cranial cruciate ligament disease, a historical cohort study

Boge, Gudrun S. and Engdahl, Karolina and Bergström, Annika and Emanuelson, Ulf and Hanson, Jeanette and Höglund, Odd and Moldal, Elena R. and Skjerve, Eystein and Krontveit, Randi (2020). Disease-related and overall survival in dogs with cranial cruciate ligament disease, a historical cohort study. Preventive Veterinary Medicine. 181 , 105057
[Journal article]

[img] PDF
297kB

Abstract

Objective: To analyse the effect of treatment method and other risk factors on survival in dogs with cranial cruciate ligament disease (CCLD).Methods: A historical cohort study of 333 dogs presenting with CCLD at two University Hospitals (2011-2016) was performed. Signalment, history, treatment and follow-up details were retrieved from medical records, dog owners and referring veterinarians. Treatment groups were defined; conservative or surgical with either lateral fabellotibial suture (LFS) or osteotomy procedures. Multivariable Cox proportional hazards models were applied to evaluate risk factors for disease-related and overall survival.Results: Sixty-five dogs were conservatively managed, 125 treated with LFS and 143 with osteotomy techniques. At follow-up (autumn 2018), 164 dogs (49.3 %) were alive and 169 (50.7 %) were dead. Both final Cox proportional hazards models included variables for treatment, age, weight and hospital. In addition, the final disease-related model included a variable for orthopaedic comorbidity, while non-orthopaedic comorbidities and a time-varying effect for age on a linear scale were included in the overall survival model. Treatment method was found to have an effect on both disease-related and overall survival and surgical treatment was associated with a lower hazard than conservative treatment.Conclusion: Survival in dogs with CCLD is influenced by treatment strategy, comorbidities, age and weight.

Authors/Creators:Boge, Gudrun S. and Engdahl, Karolina and Bergström, Annika and Emanuelson, Ulf and Hanson, Jeanette and Höglund, Odd and Moldal, Elena R. and Skjerve, Eystein and Krontveit, Randi
Title:Disease-related and overall survival in dogs with cranial cruciate ligament disease, a historical cohort study
Year of publishing :2020
Volume:181
Article number:105057
Number of Pages:7
ISSN:0167-5877
Language:English
Publication Type:Journal article
Article category:Scientific peer reviewed
Version:Published version
Copyright:Creative Commons: Attribution-Noncommercial-No Derivative Works 4.0
Full Text Status:Public
Subjects:(A) Swedish standard research categories 2011 > 4 Agricultural Sciences > 403 Veterinary Science > Clinical Science
Keywords:Stifle, TPLO, TTA, MMP, Orthopaedic, Non-surgical
URN:NBN:urn:nbn:se:slu:epsilon-p-107840
Permanent URL:
http://urn.kb.se/resolve?urn=urn:nbn:se:slu:epsilon-p-107840
Additional ID:
Type of IDID
DOI10.1016/j.prevetmed.2020.105057
Web of Science (WoS)000564719200022
ID Code:17584
Faculty:VH - Faculty of Veterinary Medicine and Animal Science
Department:(VH) > Dept. of Clinical Sciences
Deposited By: SLUpub Connector
Deposited On:24 Sep 2020 09:15
Metadata Last Modified:24 Sep 2020 09:21

Repository Staff Only: item control page

Downloads

Downloads per year (since September 2012)

View more statistics

Downloads
Hits