Boge, Gudrun S. and Engdahl, Karolina and Bergström, Annika and Emanuelson, Ulf and Hanson, Jeanette and Höglund, Odd and Moldal, Elena R. and Skjerve, Eystein and Krontveit, Randi
(2020).
Disease-related and overall survival in dogs with cranial cruciate ligament disease, a historical cohort study.
Preventive Veterinary Medicine. 181
, 105057
[Journal article]
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Abstract
Objective: To analyse the effect of treatment method and other risk factors on survival in dogs with cranial cruciate ligament disease (CCLD).Methods: A historical cohort study of 333 dogs presenting with CCLD at two University Hospitals (2011-2016) was performed. Signalment, history, treatment and follow-up details were retrieved from medical records, dog owners and referring veterinarians. Treatment groups were defined; conservative or surgical with either lateral fabellotibial suture (LFS) or osteotomy procedures. Multivariable Cox proportional hazards models were applied to evaluate risk factors for disease-related and overall survival.Results: Sixty-five dogs were conservatively managed, 125 treated with LFS and 143 with osteotomy techniques. At follow-up (autumn 2018), 164 dogs (49.3 %) were alive and 169 (50.7 %) were dead. Both final Cox proportional hazards models included variables for treatment, age, weight and hospital. In addition, the final disease-related model included a variable for orthopaedic comorbidity, while non-orthopaedic comorbidities and a time-varying effect for age on a linear scale were included in the overall survival model. Treatment method was found to have an effect on both disease-related and overall survival and surgical treatment was associated with a lower hazard than conservative treatment.Conclusion: Survival in dogs with CCLD is influenced by treatment strategy, comorbidities, age and weight.
| Authors/Creators: | Boge, Gudrun S. and Engdahl, Karolina and Bergström, Annika and Emanuelson, Ulf and Hanson, Jeanette and Höglund, Odd and Moldal, Elena R. and Skjerve, Eystein and Krontveit, Randi | ||||||
|---|---|---|---|---|---|---|---|
| Title: | Disease-related and overall survival in dogs with cranial cruciate ligament disease, a historical cohort study | ||||||
| Series Name/Journal: | Preventive Veterinary Medicine | ||||||
| Year of publishing : | 2020 | ||||||
| Volume: | 181 | ||||||
| Article number: | 105057 | ||||||
| Number of Pages: | 7 | ||||||
| ISSN: | 0167-5877 | ||||||
| Language: | English | ||||||
| Publication Type: | Journal article | ||||||
| Article category: | Scientific peer reviewed | ||||||
| Version: | Published version | ||||||
| Copyright: | Creative Commons: Attribution-Noncommercial-No Derivative Works 4.0 | ||||||
| Full Text Status: | Public | ||||||
| Subjects: | (A) Swedish standard research categories 2011 > 4 Agricultural Sciences > 403 Veterinary Science > Clinical Science | ||||||
| Keywords: | Stifle, TPLO, TTA, MMP, Orthopaedic, Non-surgical | ||||||
| URN:NBN: | urn:nbn:se:slu:epsilon-p-107840 | ||||||
| Permanent URL: | http://urn.kb.se/resolve?urn=urn:nbn:se:slu:epsilon-p-107840 | ||||||
| Additional ID: |
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| ID Code: | 17584 | ||||||
| Faculty: | VH - Faculty of Veterinary Medicine and Animal Science | ||||||
| Department: | (VH) > Dept. of Clinical Sciences | ||||||
| Deposited By: | SLUpub Connector | ||||||
| Deposited On: | 24 Sep 2020 09:15 | ||||||
| Metadata Last Modified: | 15 Jan 2021 19:18 |
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