Andersson, Elina and Kendall, Anna and Url, Angelika and Auer, Angelika and Leschnik, Michael
(2020).
The first RT-qPCR confirmed case of tick-borne encephalitis in a dog in Scandinavia.
Acta Veterinaria Scandinavica. 62
, 51
[Research article]
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Abstract
Background Tick-borne encephalitis (TBE) is a zoonotic neurological disease caused by tick-borne encephalitis virus (TBEV), a flavivirus endemic in parts of Europe and Asia. Seroconversion without signs of clinical disease is common in dogs and most of the cases previously described have been tentatively diagnosed by combining neurologic signs with serum antibody titres. Here, the first Scandinavian RT-qPCR-confirmed clinical case of TBE in a dog is reported. Case presentation A 4-year old castrated male Pointer Labrador cross was presented with acute-onset ataxia. During hospitalisation, the dog developed seizures. Despite aggressive treatment with steroids, antimicrobials and sedation/anaesthesia, there was continued deterioration during the following 24 h after admission and the dog was euthanised and submitted for necropsy. Histopathological changes in the brain were consistent with lymphoplasmacytic and histiocytic meningoencephalomyelitis. RT-qPCR examination of the brain was positive for TBEV, confirming infection. Conclusions Meningoencephalomyelitis caused by TBEV should be a diagnostic consideration in dogs presenting with clinical signs of central nervous system disease such as acute-onset ataxia and seizures in areas where TBEV-positive ticks are endemic. Clinical TBE may be underdiagnosed in dogs due to lack of specific testing.
Authors/Creators: | Andersson, Elina and Kendall, Anna and Url, Angelika and Auer, Angelika and Leschnik, Michael | ||||||
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Title: | The first RT-qPCR confirmed case of tick-borne encephalitis in a dog in Scandinavia | ||||||
Series Name/Journal: | Acta Veterinaria Scandinavica | ||||||
Year of publishing : | 2020 | ||||||
Volume: | 62 | ||||||
Article number: | 51 | ||||||
Number of Pages: | 6 | ||||||
ISSN: | 0044-605X | ||||||
Language: | English | ||||||
Publication Type: | Research article | ||||||
Article category: | Scientific peer reviewed | ||||||
Version: | Published version | ||||||
Copyright: | Creative Commons: Attribution 4.0 | ||||||
Full Text Status: | Public | ||||||
Subjects: | (A) Swedish standard research categories 2011 > 4 Agricultural Sciences > 403 Veterinary Science > Clinical Science | ||||||
Keywords: | Canine, Histopathology, Immunohistochemistry, Meningoencephalomyelitis, Necropsy, Pathology, Serology | ||||||
URN:NBN: | urn:nbn:se:slu:epsilon-p-108120 | ||||||
Permanent URL: | http://urn.kb.se/resolve?urn=urn:nbn:se:slu:epsilon-p-108120 | ||||||
Additional ID: |
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ID Code: | 17823 | ||||||
Faculty: | VH - Faculty of Veterinary Medicine and Animal Science | ||||||
Department: | (VH) > Department of Biomedical Science and Veterinary Public Health | ||||||
Deposited By: | SLUpub Connector | ||||||
Deposited On: | 14 Oct 2020 16:40 | ||||||
Metadata Last Modified: | 15 Jan 2021 19:16 |
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