Home About Browse Search
Svenska


The first RT-qPCR confirmed case of tick-borne encephalitis in a dog in Scandinavia

Andersson, Elina and Kendall, Anna and Url, Angelika and Auer, Angelika and Leschnik, Michael (2020). The first RT-qPCR confirmed case of tick-borne encephalitis in a dog in Scandinavia. Acta Veterinaria Scandinavica. 62 , 51
[Journal article]

[img] PDF
1MB

Abstract

Background Tick-borne encephalitis (TBE) is a zoonotic neurological disease caused by tick-borne encephalitis virus (TBEV), a flavivirus endemic in parts of Europe and Asia. Seroconversion without signs of clinical disease is common in dogs and most of the cases previously described have been tentatively diagnosed by combining neurologic signs with serum antibody titres. Here, the first Scandinavian RT-qPCR-confirmed clinical case of TBE in a dog is reported. Case presentation A 4-year old castrated male Pointer Labrador cross was presented with acute-onset ataxia. During hospitalisation, the dog developed seizures. Despite aggressive treatment with steroids, antimicrobials and sedation/anaesthesia, there was continued deterioration during the following 24 h after admission and the dog was euthanised and submitted for necropsy. Histopathological changes in the brain were consistent with lymphoplasmacytic and histiocytic meningoencephalomyelitis. RT-qPCR examination of the brain was positive for TBEV, confirming infection. Conclusions Meningoencephalomyelitis caused by TBEV should be a diagnostic consideration in dogs presenting with clinical signs of central nervous system disease such as acute-onset ataxia and seizures in areas where TBEV-positive ticks are endemic. Clinical TBE may be underdiagnosed in dogs due to lack of specific testing.

Authors/Creators:Andersson, Elina and Kendall, Anna and Url, Angelika and Auer, Angelika and Leschnik, Michael
Title:The first RT-qPCR confirmed case of tick-borne encephalitis in a dog in Scandinavia
Year of publishing :2020
Volume:62
Article number:51
Number of Pages:6
ISSN:0044-605X
Language:English
Publication Type:Journal article
Article category:Scientific peer reviewed
Version:Published version
Copyright:Creative Commons: Attribution 4.0
Full Text Status:Public
Subjects:(A) Swedish standard research categories 2011 > 4 Agricultural Sciences > 403 Veterinary Science > Clinical Science
Keywords:Canine, Histopathology, Immunohistochemistry, Meningoencephalomyelitis, Necropsy, Pathology, Serology
URN:NBN:urn:nbn:se:slu:epsilon-p-108120
Permanent URL:
http://urn.kb.se/resolve?urn=urn:nbn:se:slu:epsilon-p-108120
Additional ID:
Type of IDID
DOI10.1186/s13028-020-00550-2
Web of Science (WoS)000571777200001
ID Code:17823
Faculty:VH - Faculty of Veterinary Medicine and Animal Science
Department:(VH) > Department of Biomedical Science and Veterinary Public Health
Deposited By: SLUpub Connector
Deposited On:14 Oct 2020 16:40
Metadata Last Modified:14 Oct 2020 16:41

Repository Staff Only: item control page

Downloads

Downloads per year (since September 2012)

View more statistics

Downloads
Hits