Amane, Agraw and Belay, Gurja and Nasser, Yao and Kyalo, Martina and Dessie, Tadelle and Kebede, Adebabay and Getachew, Tesfaye and Entfellner, Jean-Baka Domelevo and Edea, Zewdu and Hanotte, Olivier and Tarekegn, Getinet Mekuriaw
(2020).
Genome-wide insights of Ethiopian indigenous sheep populations reveal the population structure related to tail morphology and phylogeography.
Genes and Genomics. 42
, 1169-1178
[Research article]
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Abstract
Background Ethiopian sheep living in different climatic zones and having contrasting morphologies are a most promising subject of molecular-genetic research. Elucidating their genetic diversity and genetic structure is critical for designing appropriate breeding and conservation strategies. Objective The study was aimed to investigate genome-wide genetic diversity and population structure of eight Ethiopian sheep populations. Methods A total of 115 blood samples were collected from four Ethiopian sheep populations that include Washera, Farta and Wollo (short fat-tailed) and Horro (long fat-tailed). DNA was extracted using Quick-DNA (TM) Miniprep plus kit. All DNA samples were genotyped using Ovine 50 K SNP BeadChip. To infer genetic relationships of Ethiopian sheep at national, continental and global levels, genotype data on four Ethiopian sheep (Adilo, Arsi-Bale, Menz and Black Head Somali) and sheep from east, north, and south Africa, Middle East and Asia were included in the study as reference. Results Mean genetic diversity of Ethiopian sheep populations ranged from 0.352 +/- 0.14 for Horro to 0.379 +/- 0.14 for Arsi-Bale sheep. Population structure and principal component analyses of the eight Ethiopian indigenous sheep revealed four distinct genetic cluster groups according to their tail phenotype and geographical distribution. The short fat-tailed sheep did not represent one genetic cluster group. Ethiopian fat-rump sheep share a common genetic background with the Kenyan fat-tailed sheep. Conclusion The results of the present study revealed the principal component and population structure follows a clear pattern of tail morphology and phylogeography. There is clear signature of admixture among the study Ethiopian sheep populations
| Authors/Creators: | Amane, Agraw and Belay, Gurja and Nasser, Yao and Kyalo, Martina and Dessie, Tadelle and Kebede, Adebabay and Getachew, Tesfaye and Entfellner, Jean-Baka Domelevo and Edea, Zewdu and Hanotte, Olivier and Tarekegn, Getinet Mekuriaw | ||||||
|---|---|---|---|---|---|---|---|
| Title: | Genome-wide insights of Ethiopian indigenous sheep populations reveal the population structure related to tail morphology and phylogeography | ||||||
| Series Name/Journal: | Genes and Genomics | ||||||
| Year of publishing : | 2020 | ||||||
| Volume: | 42 | ||||||
| Page range: | 1169-1178 | ||||||
| Number of Pages: | 10 | ||||||
| ISSN: | 1976-9571 | ||||||
| Language: | English | ||||||
| Publication Type: | Research article | ||||||
| Article category: | Scientific peer reviewed | ||||||
| Version: | Published version | ||||||
| Copyright: | Creative Commons: Attribution 4.0 | ||||||
| Full Text Status: | Public | ||||||
| Subjects: | (A) Swedish standard research categories 2011 > 4 Agricultural Sciences > 402 Animal and Dairy Science > Animal and Dairy Science. | ||||||
| Keywords: | Fat-tail, Genetic diversity, Ovine 50 K SNP, Population structure | ||||||
| URN:NBN: | urn:nbn:se:slu:epsilon-p-107719 | ||||||
| Permanent URL: | http://urn.kb.se/resolve?urn=urn:nbn:se:slu:epsilon-p-107719 | ||||||
| Additional ID: |
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| ID Code: | 17948 | ||||||
| Faculty: | VH - Faculty of Veterinary Medicine and Animal Science | ||||||
| Department: | (VH) > Dept. of Animal Breeding and Genetics | ||||||
| Deposited By: | SLUpub Connector | ||||||
| Deposited On: | 27 Oct 2020 11:11 | ||||||
| Metadata Last Modified: | 15 Jan 2021 19:16 |
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