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Prevalence and severity of cardiac abnormalities and arteriosclerosis in farmed rainbow trout (Oncorhynchus mykiss)

Brijs, Jeroen and Hjelmstedt, Per and Hjelmstedt, P. and Berg, Lotta and Johansen, I. B. and Sundh, H. and Roques, J. A. C. and Ekstrom, A. and Sandblom, E. and Sundell, K. and Olsson, C. and Axelsson, M. and Gräns, Albin (2020). Prevalence and severity of cardiac abnormalities and arteriosclerosis in farmed rainbow trout (Oncorhynchus mykiss). Aquaculture. 526 , 735417
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Abstract

Cardiovascular disease may pose a major threat to the health and welfare of farmed fish. By investigating a range of established cardiovascular disease indicators, we aimed to determine the prevalence, severity and consequences of this affliction in farmed rainbow trout (Oncorhynchus mykiss) from an open cage farm in the Baltic Sea, an open cage farm in a freshwater lake, and a land-based recirculating aquaculture system. We also aimed to identify environmental, anthropogenic and physiological factors contributing towards the development of the disease. The majority of trout possessed enlarged hearts with rounded ventricles (mean height:width ratios of 1.0-1.1 c.f. similar to 1.3 in wild fish) and a high degree of vessel misalignment (mean angles between the longitudinal ventricular axis and the axis of the bulbus arteriosus of 28-31 degrees c.f. similar to 23 degrees in wild fish). The prevalence and severity of coronary arteriosclerosis was also high, as 92-100% of fish from the different aquaculture facilities exhibited coronary lesions. Mean lesion incidence and severity indices were 67-95% and 3.1-3.9, respectively, which resulted in mean coronary arterial blockages of 19-32%. To evaluate the functional significance of these findings, we modelled the effects of arterial blockages on coronary blood flow and experimentally tested the effects of coronary occlusion in a sub-sample of fish. The observed coronary blockages were estimated to reduce coronary blood flow by 34-54% while experimental coronary occlusion adversely affected the electrocardiogram of trout. Across a range of environmental (water current, predation), anthropogenic (boat traffic intensity, hatchery of origin, brand of feed pellets) and physiological factors (condition factor, haematological and plasma indices), the hatchery of origin was the main factor contributing towards the observed variation in the development of cardiovascular disease. Therefore, further research on the effects of selective breeding programs and rearing strategies on the development of cardiovascular disease is needed to improve the welfare and health of farmed fish.

Authors/Creators:Brijs, Jeroen and Hjelmstedt, Per and Hjelmstedt, P. and Berg, Lotta and Johansen, I. B. and Sundh, H. and Roques, J. A. C. and Ekstrom, A. and Sandblom, E. and Sundell, K. and Olsson, C. and Axelsson, M. and Gräns, Albin
Title:Prevalence and severity of cardiac abnormalities and arteriosclerosis in farmed rainbow trout (Oncorhynchus mykiss)
Year of publishing :2020
Volume:526
Article number:735417
Number of Pages:11
Publisher:ELSEVIER
ISSN:0044-8486
Language:English
Publication Type:Journal article
Article category:Scientific peer reviewed
Version:Published version
Copyright:Creative Commons: Attribution 4.0
Full Text Status:Public
Subjects:(A) Swedish standard research categories 2011 > 4 Agricultural Sciences > 401 Agricultural, Forestry and Fisheries > Fish and Aquacultural Science
Keywords:Arteriosclerosis, Coronary artery, ECG, Heart morphology, Stress physiology
URN:NBN:urn:nbn:se:slu:epsilon-p-108398
Permanent URL:
http://urn.kb.se/resolve?urn=urn:nbn:se:slu:epsilon-p-108398
Additional ID:
Type of IDID
DOI10.1016/j.aquaculture.2020.735417
Web of Science (WoS)000536865800012
ID Code:18078
Faculty:VH - Faculty of Veterinary Medicine and Animal Science
Department:(VH) > Dept. of Animal Environment and Health
Deposited By: SLUpub Connector
Deposited On:05 Nov 2020 09:03
Metadata Last Modified:05 Nov 2020 09:11

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