Home About Browse Search
Svenska


HEARTBREAK Controls Post-translational Modification of INDEHISCENT to Regulate Fruit Morphology in Capsella

Dong, Yang and Majda, Mateusz and Simura, Jan and Horvath, Robert and Srivastava, Anjil K. and Langowski, Lukasz and Eldridge, Tilly and Stacey, Nicola and Slotte, Tanja and Sadanandom, Ari and Ljung, Karin and Smith, Richard S. and Ostergaard, Lars (2020). HEARTBREAK Controls Post-translational Modification of INDEHISCENT to Regulate Fruit Morphology in Capsella. Current Biology. 30 , 3880-3888
[Journal article]

[img] PDF
5MB

Abstract

Morphological variation is the basis of natural diversity and adaptation. For example, angiosperms (flowering plants) evolved during the Cretaceous period more than 100 mya and quickly colonized terrestrial habitats [1]. A major reason for their astonishing success was the formation of fruits, which exist in a myriad of different shapes and sizes [2]. Evolution of organ shape is fueled by variation in expression patterns of regulatory genes causing changes in anisotropic cell expansion and division patterns [3-5]. However, the molecular mechanisms that alter the polarity of growth to generate novel shapes are largely unknown. The heart-shaped fruits produced by members of the Capsella genus comprise an anatomical novelty, making it particularly well suited for studies on morphological diversification [6-8]. Here, we show that post-translational modification of regulatory proteins provides a critical step in organ-shape formation. Our data reveal that the SUMO protease, HEARTBREAK (HTB), from Capsella rubella controls the activity of the key regulator of fruit development, INDEHISCENT (CrIND in C. rubella), via de-SUMOylation. This post-translational modification initiates a transduction pathway required to ensure precisely localized auxin biosynthesis, thereby facilitating anisotropic cell expansion to ultimately form the heart-shaped Capsella fruit. Therefore, although variation in the expression of key regulatory genes is known to be a primary driver in morphological evolution, our work demonstrates how other processes-such as post-translational modification of one such regulator-affects organ morphology.

Authors/Creators:Dong, Yang and Majda, Mateusz and Simura, Jan and Horvath, Robert and Srivastava, Anjil K. and Langowski, Lukasz and Eldridge, Tilly and Stacey, Nicola and Slotte, Tanja and Sadanandom, Ari and Ljung, Karin and Smith, Richard S. and Ostergaard, Lars
Title:HEARTBREAK Controls Post-translational Modification of INDEHISCENT to Regulate Fruit Morphology in Capsella
Year of publishing :2020
Volume:30
Page range:3880-3888
Number of Pages:14
Publisher:CELL PRESS
ISSN:0960-9822
Language:English
Publication Type:Journal article
Article category:Scientific peer reviewed
Version:Published version
Copyright:Creative Commons: Attribution 4.0
Full Text Status:Public
Subjects:(A) Swedish standard research categories 2011 > 1 Natural sciences > 106 Biological Sciences (Medical to be 3 and Agricultural to be 4) > Developmental Biology
URN:NBN:urn:nbn:se:slu:epsilon-p-108671
Permanent URL:
http://urn.kb.se/resolve?urn=urn:nbn:se:slu:epsilon-p-108671
Additional ID:
Type of IDID
DOI10.1016/j.cub.2020.07.055
Web of Science (WoS)000579845200057
ID Code:18684
Faculty:S - Faculty of Forest Sciences
Department:(S) > Dept. of Forest Genetics and Plant Physiology
Deposited By: SLUpub Connector
Deposited On:17 Nov 2020 16:23
Metadata Last Modified:17 Nov 2020 16:31

Repository Staff Only: item control page

Downloads

Downloads per year (since September 2012)

View more statistics

Downloads
Hits