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Total mercury in hair as biomarker for methylmercury exposure among women in central Sweden - a 23 year long temporal trend study

Kippler, Maria and Gyllenhammar, Irina and Glynn, Anders and Levi, Michael and Lignell, Sanna and Berglund, Marika (2021). Total mercury in hair as biomarker for methylmercury exposure among women in central Sweden - a 23 year long temporal trend study. Environmental Pollution. 268 , 115712
[Research article]

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Abstract

Exposure to methylmercury (MeHg) through fish is a global public health problem. Exposure monitoring is essential for health risk assessment, especially in pregnant women and children due to the documented neurotoxicity. Herein, we evaluate a time series of MeHg exposure via fish in primiparous Swedish women, covering a time period of 23 years (1996-2019). The 655 included mothers were part of the POPUP study (Persistent Organic Pollutants in Uppsala Primiparas) conducted by the Swedish Food Agency (SFA). MeHg exposure was assessed via measurements of total mercury (Hg) in hair using either cold vapor atomic fluorescence spectrophotometry or inductively coupled plasma mass spectrometry, showing very good linear agreement (R-2 = 0.97). Maternal characteristics and fish consumption were obtained via questionnaires. The median concentration of total Hg in hair was 0.38 mg/kg (range 0.17 -1.5) in 1996 and 0.25 mg/kg (range 0.03-1.1) in 2019. On average the women consumed 11 8.2 meals of fish per month, and fish consumption was positively correlated with total Hg in hair (Spearman correlation: 0.39; p < 0.001). In multiple regression analyses, the geometric mean annual decrease of total Hg in hair was -2.5% (95% CI: -3.2, -1.8%). Total fish consumption increased up to 2011 (B: 0.32 times/month per year; 95% CI 0.17, 0.46) after which it started to decline (B: -0.66 times/month per year; 95% CI -0.92, -0.40). Moreover, both total Hg in hair and fish consumption was positively associated with maternal age and education, and inversely associated with pre-pregnancy BMI. In conclusion, the exposure to MeHg via fish appears to be slowly declining among Swedish pregnant women. (C) 2020 The Author(s). Published by Elsevier Ltd.

Authors/Creators:Kippler, Maria and Gyllenhammar, Irina and Glynn, Anders and Levi, Michael and Lignell, Sanna and Berglund, Marika
Title:Total mercury in hair as biomarker for methylmercury exposure among women in central Sweden - a 23 year long temporal trend study
Series Name/Journal:Environmental Pollution
Year of publishing :2021
Volume:268
Article number:115712
Number of Pages:8
Publisher:ELSEVIER SCI LTD
ISSN:0269-7491
Language:English
Publication Type:Research article
Article category:Scientific peer reviewed
Version:Published version
Copyright:Creative Commons: Attribution 4.0
Full Text Status:Public
Subjects:(A) Swedish standard research categories 2011 > 1 Natural sciences > 105 Earth and Related Environmental Sciences > Environmental Sciences (social aspects to be 507)
Keywords:Methylmercury, Hair, Exposure assessment, Biomarker, ICPMS, Temporal trend
URN:NBN:urn:nbn:se:slu:epsilon-p-110344
Permanent URL:
http://urn.kb.se/resolve?urn=urn:nbn:se:slu:epsilon-p-110344
Additional ID:
Type of IDID
DOI10.1016/j.envpol.2020.115712
Web of Science (WoS)000600553000118
ID Code:21808
Faculty:VH - Faculty of Veterinary Medicine and Animal Science
Department:(VH) > Department of Biomedical Science and Veterinary Public Health
Deposited By: SLUpub Connector
Deposited On:01 Feb 2021 09:23
Metadata Last Modified:01 Feb 2021 09:31

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