Pringle, John and Venner, Monica and Tscheschlok, Lisa and Waller, Andrew S. and Riihimäki, Miia
(2020).
Markers of long term silent carriers of Streptococcus equiss p.equiin horses.
Journal of Veterinary Internal Medicine. 34
, 2751-2757
[Research article]
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Abstract
Background Difficulty in detection of silent carriers ofStreptococcus equiis a key reason for its continued spread to immunologically naive groups of horses. Objective To determine whether clinical examination, markers of inflammation, or serology differentiate silent carriers ofS. equiin recovered comingled horses. Animals Ninety-eight warmblood yearlings and 72 unaffected mares on a large breeding farm (outbreak A), 38 mature Icelandic horses at a riding stable (outbreak B), and 27 mixed breed horses at a boarding stable (outbreak C). Methods Prospective observational study 6 months to 2 years after strangles outbreaks. Carriers were defined as any animal positive on culture or qPCR toS. equifrom nasopharyngeal lavage or guttural pouch endoscopy and lavage. Most horses had complete physical exams and 1 group included evaluation of white blood cell counts and serum amyloid A. Sera from all horses was tested for antibodies to antigens A and C ofS. equiusing an enhanced indirect ELISA. Descriptive statistics were calculated. Data were compared using pairedttests, Wilcoxon ranked test, chi square, or the Fishers exact test. Significance was set atP < .05. Results Apart from weanlings at 6 months in outbreak A, there was no significant association between any clinical markers or serology with carrier state (P= .06-1). Moreover, 3/12 culture positive carriers were seronegative toS. equi. Conclusions and Clinical Importance Silent carriers ofS. equido not differ clinically or on markers of inflammation to their noncarrier herd-mates. Moreover, serology alone will not distinguish carriers in comingled horses.
Authors/Creators: | Pringle, John and Venner, Monica and Tscheschlok, Lisa and Waller, Andrew S. and Riihimäki, Miia | ||||||
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Title: | Markers of long term silent carriers of Streptococcus equiss p.equiin horses | ||||||
Series Name/Journal: | Journal of Veterinary Internal Medicine | ||||||
Year of publishing : | 2020 | ||||||
Volume: | 34 | ||||||
Page range: | 2751-2757 | ||||||
Number of Pages: | 7 | ||||||
Publisher: | WILEY | ||||||
ISSN: | 0891-6640 | ||||||
Language: | English | ||||||
Publication Type: | Research article | ||||||
Article category: | Scientific peer reviewed | ||||||
Version: | Published version | ||||||
Copyright: | Creative Commons: Attribution 4.0 | ||||||
Full Text Status: | Public | ||||||
Subjects: | (A) Swedish standard research categories 2011 > 4 Agricultural Sciences > 403 Veterinary Science > Clinical Science | ||||||
Keywords: | antigen A, antigen C, silent carrier, equine, iELISA, infection | ||||||
URN:NBN: | urn:nbn:se:slu:epsilon-p-108645 | ||||||
Permanent URL: | http://urn.kb.se/resolve?urn=urn:nbn:se:slu:epsilon-p-108645 | ||||||
Additional ID: |
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ID Code: | 21949 | ||||||
Faculty: | VH - Faculty of Veterinary Medicine and Animal Science | ||||||
Department: | (VH) > Dept. of Clinical Sciences | ||||||
Deposited By: | SLUpub Connector | ||||||
Deposited On: | 03 Feb 2021 04:23 | ||||||
Metadata Last Modified: | 03 Feb 2021 06:01 |
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