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New extraction method prior to screening of organic micropollutants in various biota matrices using liquid chromatography coupled to high-resolution time-of-flight mass spectrometry

Dürig, Wiebke and Kintzi, Aaron and Golovko, Oksana and Wiberg, Karin and Ahrens, Lutz (2020). New extraction method prior to screening of organic micropollutants in various biota matrices using liquid chromatography coupled to high-resolution time-of-flight mass spectrometry. Talanta. 219 , 121294
[Journal article]

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Abstract

A new extraction method with limited clean-up requirements prior to screening various matrices for organic micropollutants using liquid chromatography-high resolution mass spectrometry (LC-HRMS) for analysis was developed. First, the performance of three extraction methods (QuEChERS with SPE clean-up, ultrasonication with SPE clean-up, extraction without SPE clean-up) was tested, optimized, and compared using > 200 contaminants of emerging concern (CECs) together covering a wide range of physicochemical properties applicable for suspect and non-target screening in biota. White-tailed sea eagle (Haliaeetus albicilla) muscle tissue was used in method development and optimization. The method without SPE clean-up was then applied to European perch (Perca fluviatilis) muscle, heart, and liver tissues. The optimization and application of the method demonstrated a wide applicable domain of the novel extraction method regarding species, tissues, and chemicals. For future applications, the suitability of the method for suspect and non-target screening was tested. Overall, our extraction method appears to be sufficiently simple and broad (relatively non-discriminant) for use prior to analysis of CECs in various biota.

Authors/Creators:Dürig, Wiebke and Kintzi, Aaron and Golovko, Oksana and Wiberg, Karin and Ahrens, Lutz
Title:New extraction method prior to screening of organic micropollutants in various biota matrices using liquid chromatography coupled to high-resolution time-of-flight mass spectrometry
Series Name/Journal:Talanta
Year of publishing :2020
Volume:219
Article number:121294
Number of Pages:8
Publisher:ELSEVIER
ISSN:0039-9140
Language:English
Publication Type:Journal article
Article category:Scientific peer reviewed
Version:Published version
Copyright:Creative Commons: Attribution-Noncommercial-No Derivative Works 4.0
Full Text Status:Public
Subjects:(A) Swedish standard research categories 2011 > 1 Natural sciences > 104 Chemical Sciences > Analytical Chemistry
Keywords:Extraction method, Biota, Clean-up, LC-QToF-MS, Suspect and non-target screening, White-tailed sea eagle
URN:NBN:urn:nbn:se:slu:epsilon-p-108034
Permanent URL:
http://urn.kb.se/resolve?urn=urn:nbn:se:slu:epsilon-p-108034
Additional ID:
Type of IDID
DOI10.1016/j.talanta.2020.121294
Web of Science (WoS)000568750500009
ID Code:21989
Faculty:NJ - Fakulteten för naturresurser och jordbruksvetenskap
Department:(NL, NJ) > Dept. of Aquatic Sciences and Assessment
Deposited By: SLUpub Connector
Deposited On:03 Feb 2021 12:23
Metadata Last Modified:03 Feb 2021 12:31

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