Dürig, Wiebke and Kintzi, Aaron and Golovko, Oksana and Wiberg, Karin and Ahrens, Lutz
(2020).
New extraction method prior to screening of organic micropollutants in various biota matrices using liquid chromatography coupled to high-resolution time-of-flight mass spectrometry.
Talanta. 219
, 121294
[Research article]
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Abstract
A new extraction method with limited clean-up requirements prior to screening various matrices for organic micropollutants using liquid chromatography-high resolution mass spectrometry (LC-HRMS) for analysis was developed. First, the performance of three extraction methods (QuEChERS with SPE clean-up, ultrasonication with SPE clean-up, extraction without SPE clean-up) was tested, optimized, and compared using > 200 contaminants of emerging concern (CECs) together covering a wide range of physicochemical properties applicable for suspect and non-target screening in biota. White-tailed sea eagle (Haliaeetus albicilla) muscle tissue was used in method development and optimization. The method without SPE clean-up was then applied to European perch (Perca fluviatilis) muscle, heart, and liver tissues. The optimization and application of the method demonstrated a wide applicable domain of the novel extraction method regarding species, tissues, and chemicals. For future applications, the suitability of the method for suspect and non-target screening was tested. Overall, our extraction method appears to be sufficiently simple and broad (relatively non-discriminant) for use prior to analysis of CECs in various biota.
| Authors/Creators: | Dürig, Wiebke and Kintzi, Aaron and Golovko, Oksana and Wiberg, Karin and Ahrens, Lutz | ||||||
|---|---|---|---|---|---|---|---|
| Title: | New extraction method prior to screening of organic micropollutants in various biota matrices using liquid chromatography coupled to high-resolution time-of-flight mass spectrometry | ||||||
| Series Name/Journal: | Talanta | ||||||
| Year of publishing : | 2020 | ||||||
| Volume: | 219 | ||||||
| Article number: | 121294 | ||||||
| Number of Pages: | 8 | ||||||
| Publisher: | ELSEVIER | ||||||
| ISSN: | 0039-9140 | ||||||
| Language: | English | ||||||
| Publication Type: | Research article | ||||||
| Article category: | Scientific peer reviewed | ||||||
| Version: | Published version | ||||||
| Copyright: | Creative Commons: Attribution-Noncommercial-No Derivative Works 4.0 | ||||||
| Full Text Status: | Public | ||||||
| Subjects: | (A) Swedish standard research categories 2011 > 1 Natural sciences > 104 Chemical Sciences > Analytical Chemistry | ||||||
| Keywords: | Extraction method, Biota, Clean-up, LC-QToF-MS, Suspect and non-target screening, White-tailed sea eagle | ||||||
| URN:NBN: | urn:nbn:se:slu:epsilon-p-108034 | ||||||
| Permanent URL: | http://urn.kb.se/resolve?urn=urn:nbn:se:slu:epsilon-p-108034 | ||||||
| Additional ID: |
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| ID Code: | 21989 | ||||||
| Faculty: | NJ - Fakulteten för naturresurser och jordbruksvetenskap | ||||||
| Department: | (NL, NJ) > Dept. of Aquatic Sciences and Assessment | ||||||
| Deposited By: | SLUpub Connector | ||||||
| Deposited On: | 03 Feb 2021 12:23 | ||||||
| Metadata Last Modified: | 03 Feb 2021 12:31 |
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