Home About Browse Search
Svenska


Scientific Opinion on Flavouring Group Evaluation 73, Revision 5 (FGE.73Rev5): consideration of acyclic alcohols, aldehydes, acids and related esters evaluated by JECFA (59th, 63rd and 86th meeting) structurally related to substances evaluated in FGE.12Rev5

Younes, Maged and Aquilina, Gabriele and Castle, Laurence and Engel, Karl‐Heinz and Fowler, Paul and Frutos Fernandez, Maria Jose and Fürst, Peter and Gundert‐Remy, Ursula and Gürtler, Rainer and Husøy, Trine and Moldeus, Peter and Oskarsson, Agneta and Shah, Romina and Waalkens‐Berendsen, Ine and Wölfe, Detlef and Benigni, Romualdo and Bolognesi, Claudia and Chipman, Kevin and Cordelli, Eugenia and Degen, Gisela and Marzin, Daniel and Svendsen, Camilla and Carfí, Maria and Martino, Carla and Mennes, Wim (2020). Scientific Opinion on Flavouring Group Evaluation 73, Revision 5 (FGE.73Rev5): consideration of acyclic alcohols, aldehydes, acids and related esters evaluated by JECFA (59th, 63rd and 86th meeting) structurally related to substances evaluated in FGE.12Rev5. EFSA Journal. 18 , e05970
[Journal article]

[img] PDF
3MB

Abstract

The EFSA Panel on Food Additives and Flavourings was requested to evaluate 24 flavouring substances assigned to the Flavouring Group Evaluation 73 (FGE.73), using the Procedure as outlined in the Commission Regulation (EC) No 1565/2000. Twenty‐three substances have already been considered in FGE.73 and its four revisions ([FL‐no: 02.114, 02.141, 05.098, 05.112, 08.067, 09.289, 09.488, 09.534, 09.615, 05.119, 05.123, 08.034, 08.060, 09.028, 09.536, 05.104, 09.034, 09.712, 09.305, 02.060, 02.091, 09.278, 09.302]). The remaining substance myrtenal [FL‐no: 05.106] has been cleared with respect to genotoxicity in FGE.208Rev3 and is considered in this revision 5 of FGE.73. The substances were evaluated through a stepwise approach that integrates information on the structure–activity relationships, intake from current uses, toxicological threshold of concern (TTC), and available data on metabolism and toxicity. The Panel concluded that none of these 24 substances gives rise to safety concerns at their levels of dietary intake, estimated on the basis of the ‘Maximised Survey‐derived Daily Intake’ (MSDI) approach. Besides the safety assessment of the flavouring substances, the specifications for the materials of commerce have also been considered and found adequate for 23 substances. For [FL‐no: 09.278], the stereoisomeric composition is not specified. For two substances [FL‐no: 09.034, and 09.712], the modified Theoretical Added Maximum Daily Intake (mTAMDI) estimates are above the TTC for their structural class (I). For 17 substances evaluated through the Procedure, no normal and maximum use levels are available. Therefore, for these 19 substances, more detailed data on uses and use levels should be provided in order to refine their exposure assessments and to finalise their safety evaluations.

Authors/Creators:Younes, Maged and Aquilina, Gabriele and Castle, Laurence and Engel, Karl‐Heinz and Fowler, Paul and Frutos Fernandez, Maria Jose and Fürst, Peter and Gundert‐Remy, Ursula and Gürtler, Rainer and Husøy, Trine and Moldeus, Peter and Oskarsson, Agneta and Shah, Romina and Waalkens‐Berendsen, Ine and Wölfe, Detlef and Benigni, Romualdo and Bolognesi, Claudia and Chipman, Kevin and Cordelli, Eugenia and Degen, Gisela and Marzin, Daniel and Svendsen, Camilla and Carfí, Maria and Martino, Carla and Mennes, Wim
Title:Scientific Opinion on Flavouring Group Evaluation 73, Revision 5 (FGE.73Rev5): consideration of acyclic alcohols, aldehydes, acids and related esters evaluated by JECFA (59th, 63rd and 86th meeting) structurally related to substances evaluated in FGE.12Rev5
Series Name/Journal:EFSA Journal
Year of publishing :2020
Volume:18
Article number:e05970
Number of Pages:31
ISSN:1831-4732
Language:English
Publication Type:Journal article
Article category:Scientific peer reviewed
Version:Published version
Copyright:Creative Commons: Attribution-No Derivative Works 4.0
Full Text Status:Public
Subjects:(A) Swedish standard research categories 2011 > 3 Medical and Health Sciences > 303 Health Sciences > Public Health, Global Health, Social Medicine and Epidemiology
(A) Swedish standard research categories 2011 > 4 Agricultural Sciences > 401 Agricultural, Forestry and Fisheries > Food Science
Keywords:Flavourings, Myrtenal, a,b-unsaturated carbonyls, FGE.73 Rev4, JECFA
URN:NBN:urn:nbn:se:slu:epsilon-p-110060
Permanent URL:
http://urn.kb.se/resolve?urn=urn:nbn:se:slu:epsilon-p-110060
Additional ID:
Type of IDID
DOI10.2903/j.efsa.2020.5970
ID Code:22643
Faculty:VH - Faculty of Veterinary Medicine and Animal Science
Department:(VH) > Department of Biomedical Science and Veterinary Public Health
Deposited By: SLUpub Connector
Deposited On:23 Feb 2021 08:23
Metadata Last Modified:01 Mar 2021 02:46

Repository Staff Only: item control page

Downloads

Downloads per year (since September 2012)

View more statistics

Downloads
Hits