Home About Browse Search
Svenska


Dogs as Sentinels for Flavivirus Exposure in Urban, Peri-Urban and Rural Hanoi, Vietnam

Pham-Thanh, Long and Nguyen-Tien, Thang and Magnusson, Ulf and Bui-Nghia, Vuong and Bui-Ngoc, Anh and Le-Thanh, Duy and Lundkvist, Ake and Can-Xuan, Minh and Nguyen-Thi Thu, Thuy and Vu-Thi Bich, Hau and Lee, Hu Suk and Nguyen-Viet, Hung and Lindahl, Johanna (2021). Dogs as Sentinels for Flavivirus Exposure in Urban, Peri-Urban and Rural Hanoi, Vietnam. Viruses. 13 , 507
[Research article]

[img] PDF
668kB

Abstract

Diseases caused by flaviviruses, including dengue fever and Japanese encephalitis, are major health problems in Vietnam. This cross-sectional study explored the feasibility of domestic dogs as sentinels to better understand risks of mosquito-borne diseases in Hanoi city. A total of 475 dogs serum samples from 221 households in six districts of Hanoi were analyzed by a competitive enzyme-linked immunosorbent assay (cELISA) for antibodies to the pr-E protein of West Nile virus and other flaviviruses due to cross-reactivity. The overall flavivirus seroprevalence in the dog population was 70.7% (95% CI = 66.4-74.8%). At the animal level, significant associations between seropositive dogs and district location, age, breed and keeping practice were determined. At the household level, the major risk factors were rural and peri-urban locations, presence of pigs, coil burning and households without mosquito-borne disease experience (p < 0.05). Mosquito control by using larvicides or electric traps could lower seropositivity, but other measures did not contribute to significant risk mitigation of flavivirus exposure in dogs. These results will support better control of mosquito-borne diseases in Hanoi, and they indicate that dogs can be used as sentinels for flavivirus exposure.

Authors/Creators:Pham-Thanh, Long and Nguyen-Tien, Thang and Magnusson, Ulf and Bui-Nghia, Vuong and Bui-Ngoc, Anh and Le-Thanh, Duy and Lundkvist, Ake and Can-Xuan, Minh and Nguyen-Thi Thu, Thuy and Vu-Thi Bich, Hau and Lee, Hu Suk and Nguyen-Viet, Hung and Lindahl, Johanna
Title:Dogs as Sentinels for Flavivirus Exposure in Urban, Peri-Urban and Rural Hanoi, Vietnam
Series Name/Journal:Viruses
Year of publishing :2021
Volume:13
Article number:507
Number of Pages:11
Publisher:MDPI
ISSN:1999-4915
Language:English
Publication Type:Research article
Article category:Scientific peer reviewed
Version:Published version
Copyright:Creative Commons: Attribution 4.0
Full Text Status:Public
Subjects:(A) Swedish standard research categories 2011 > 3 Medical and Health Sciences > 303 Health Sciences > Public Health, Global Health, Social Medicine and Epidemiology
Keywords:dogs, mosquito-borne flavivirus, seroprevalence, Hanoi, Vietnam
URN:NBN:urn:nbn:se:slu:epsilon-p-111624
Permanent URL:
http://urn.kb.se/resolve?urn=urn:nbn:se:slu:epsilon-p-111624
Additional ID:
Type of IDID
DOI10.3390/v13030507
Web of Science (WoS)000634234800001
ID Code:23387
Faculty:VH - Faculty of Veterinary Medicine and Animal Science
Department:(VH) > Dept. of Clinical Sciences
Deposited By: SLUpub Connector
Deposited On:03 May 2021 14:23
Metadata Last Modified:03 May 2021 14:31

Repository Staff Only: item control page

Downloads

Downloads per year (since September 2012)

View more statistics

Downloads
Hits