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You Had Me at "MAGIC"!: Four Barley MAGIC Populations Reveal Novel Resistance QTL for Powdery Mildew

Novakazi, Fluturë and Krusell, Lene and Jensen, Jens Due and Orabi, Jihad and Jahoor, Ahmed and Bengtsson, Therese (2020). You Had Me at "MAGIC"!: Four Barley MAGIC Populations Reveal Novel Resistance QTL for Powdery Mildew. Genes. 11 , 1512
[Research article]

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Abstract

Blumeria graminis f. sp. hordei (Bgh), the causal agent of barley powdery mildew (PM), is one of the most important barley leaf diseases and is prevalent in most barley growing regions. Infection decreases grain quality and yields on average by 30%. Multi-parent advanced generation inter-cross (MAGIC) populations combine the advantages of bi-parental and association panels and offer the opportunity to incorporate exotic alleles into adapted material. Here, four barley MAGIC populations consisting of six to eight founders were tested for PM resistance in field trials in Denmark. Principle component and STRUCTURE analysis showed the populations were unstructured and genome-wide linkage disequilibrium (LD) decay varied between 14 and 38 Mbp. Genome-wide association studies (GWAS) identified 11 regions associated with PM resistance located on chromosomes 1H, 2H, 3H, 4H, 5H and 7H, of which three regions are putatively novel resistance quantitative trait locus/loci (QTL). For all regions high-confidence candidate genes were identified that are predicted to be involved in pathogen defense. Haplotype analysis of the significant SNPs revealed new allele combinations not present in the founders and associated with high resistance levels.

Authors/Creators:Novakazi, Fluturë and Krusell, Lene and Jensen, Jens Due and Orabi, Jihad and Jahoor, Ahmed and Bengtsson, Therese
Title:You Had Me at "MAGIC"!: Four Barley MAGIC Populations Reveal Novel Resistance QTL for Powdery Mildew
Series Name/Journal:Genes
Year of publishing :2020
Volume:11
Article number:1512
Number of Pages:21
Publisher:MDPI
ISSN:2073-4425
Language:English
Publication Type:Research article
Article category:Scientific peer reviewed
Version:Published version
Copyright:Creative Commons: Attribution 4.0
Full Text Status:Public
Subjects:(A) Swedish standard research categories 2011 > 4 Agricultural Sciences > 404 Agricultural Biotechnology > Genetics and Breeding
Keywords:Blumeria graminis f. sp. hordei, GWAS, Hordeum vulgare L., linkage disequilibrium, multi-locus mixed linear model, multi-parent advanced generation inter-cross, plant breeding
URN:NBN:urn:nbn:se:slu:epsilon-p-110212
Permanent URL:
http://urn.kb.se/resolve?urn=urn:nbn:se:slu:epsilon-p-110212
Additional ID:
Type of IDID
DOI10.3390/genes11121512
Web of Science (WoS)000601933400001
ID Code:23402
Faculty:LTV - Fakulteten för landskapsarkitektur, trädgårds- och växtproduktionsvetenskap
Department:(LTJ, LTV) > Department of Plant Breeding (from 130101)
Deposited By: SLUpub Connector
Deposited On:03 May 2021 19:43
Metadata Last Modified:04 May 2021 05:01

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