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Pickle Recruits Retinoblastoma Related 1 to Control Lateral Root Formation in Arabidopsis

Otvos, Krisztina and Miskolczi, Pal Csaba and Marhavy, Peter and Cruz-Ramirez, Alfredo and Benkova, Eva and Robert, Stephanie and Bako, Laszlo (2021). Pickle Recruits Retinoblastoma Related 1 to Control Lateral Root Formation in Arabidopsis. International Journal of Molecular Sciences. 22 , 3862
[Research article]

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Abstract

Lateral root (LR) formation is an example of a plant post-embryonic organogenesis event. LRs are issued from non-dividing cells entering consecutive steps of formative divisions, proliferation and elongation. The chromatin remodeling protein PICKLE (PKL) negatively regulates auxin-mediated LR formation through a mechanism that is not yet known. Here we show that PKL interacts with RETINOBLASTOMA-RELATED 1 (RBR1) to repress the LATERAL ORGAN BOUNDARIES-DOMAIN 16 (LBD16) promoter activity. Since LBD16 function is required for the formative division of LR founder cells, repression mediated by the PKL-RBR1 complex negatively regulates formative division and LR formation. Inhibition of LR formation by PKL-RBR1 is counteracted by auxin, indicating that, in addition to auxin-mediated transcriptional responses, the fine-tuned process of LR formation is also controlled at the chromatin level in an auxin-signaling dependent manner.

Authors/Creators:Otvos, Krisztina and Miskolczi, Pal Csaba and Marhavy, Peter and Cruz-Ramirez, Alfredo and Benkova, Eva and Robert, Stephanie and Bako, Laszlo
Title:Pickle Recruits Retinoblastoma Related 1 to Control Lateral Root Formation in Arabidopsis
Series Name/Journal:International Journal of Molecular Sciences
Year of publishing :2021
Volume:22
Article number:3862
Number of Pages:17
Publisher:MDPI
ISSN:1661-6596
Language:English
Publication Type:Research article
Article category:Scientific peer reviewed
Version:Published version
Copyright:Creative Commons: Attribution 4.0
Full Text Status:Public
Subjects:(A) Swedish standard research categories 2011 > 1 Natural sciences > 106 Biological Sciences (Medical to be 3 and Agricultural to be 4) > Biochemistry and Molecular Biology
(A) Swedish standard research categories 2011 > 1 Natural sciences > 106 Biological Sciences (Medical to be 3 and Agricultural to be 4) > Botany
Keywords:chromatin remodeling, auxin signaling, de novo organogenesis
URN:NBN:urn:nbn:se:slu:epsilon-p-111948
Permanent URL:
http://urn.kb.se/resolve?urn=urn:nbn:se:slu:epsilon-p-111948
Additional ID:
Type of IDID
DOI10.3390/ijms22083862
Web of Science (WoS)000644394800001
ID Code:23919
Faculty:S - Faculty of Forest Sciences
Department:(S) > Dept. of Forest Genetics and Plant Physiology
Deposited By: SLUpub Connector
Deposited On:27 May 2021 13:43
Metadata Last Modified:27 May 2021 13:51

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