Otvos, Krisztina and Miskolczi, Pal Csaba and Marhavy, Peter and Cruz-Ramirez, Alfredo and Benkova, Eva and Robert, Stephanie and Bako, Laszlo
(2021).
Pickle Recruits Retinoblastoma Related 1 to Control Lateral Root Formation in Arabidopsis.
International Journal of Molecular Sciences. 22
, 3862
[Research article]
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Abstract
Lateral root (LR) formation is an example of a plant post-embryonic organogenesis event. LRs are issued from non-dividing cells entering consecutive steps of formative divisions, proliferation and elongation. The chromatin remodeling protein PICKLE (PKL) negatively regulates auxin-mediated LR formation through a mechanism that is not yet known. Here we show that PKL interacts with RETINOBLASTOMA-RELATED 1 (RBR1) to repress the LATERAL ORGAN BOUNDARIES-DOMAIN 16 (LBD16) promoter activity. Since LBD16 function is required for the formative division of LR founder cells, repression mediated by the PKL-RBR1 complex negatively regulates formative division and LR formation. Inhibition of LR formation by PKL-RBR1 is counteracted by auxin, indicating that, in addition to auxin-mediated transcriptional responses, the fine-tuned process of LR formation is also controlled at the chromatin level in an auxin-signaling dependent manner.
| Authors/Creators: | Otvos, Krisztina and Miskolczi, Pal Csaba and Marhavy, Peter and Cruz-Ramirez, Alfredo and Benkova, Eva and Robert, Stephanie and Bako, Laszlo | ||||||
|---|---|---|---|---|---|---|---|
| Title: | Pickle Recruits Retinoblastoma Related 1 to Control Lateral Root Formation in Arabidopsis | ||||||
| Series Name/Journal: | International Journal of Molecular Sciences | ||||||
| Year of publishing : | 2021 | ||||||
| Volume: | 22 | ||||||
| Article number: | 3862 | ||||||
| Number of Pages: | 17 | ||||||
| Publisher: | MDPI | ||||||
| ISSN: | 1661-6596 | ||||||
| Language: | English | ||||||
| Publication Type: | Research article | ||||||
| Article category: | Scientific peer reviewed | ||||||
| Version: | Published version | ||||||
| Copyright: | Creative Commons: Attribution 4.0 | ||||||
| Full Text Status: | Public | ||||||
| Subjects: | (A) Swedish standard research categories 2011 > 1 Natural sciences > 106 Biological Sciences (Medical to be 3 and Agricultural to be 4) > Biochemistry and Molecular Biology (A) Swedish standard research categories 2011 > 1 Natural sciences > 106 Biological Sciences (Medical to be 3 and Agricultural to be 4) > Botany | ||||||
| Keywords: | chromatin remodeling, auxin signaling, de novo organogenesis | ||||||
| URN:NBN: | urn:nbn:se:slu:epsilon-p-111948 | ||||||
| Permanent URL: | http://urn.kb.se/resolve?urn=urn:nbn:se:slu:epsilon-p-111948 | ||||||
| Additional ID: |
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| ID Code: | 23919 | ||||||
| Faculty: | S - Faculty of Forest Sciences | ||||||
| Department: | (S) > Dept. of Forest Genetics and Plant Physiology | ||||||
| Deposited By: | SLUpub Connector | ||||||
| Deposited On: | 27 May 2021 13:43 | ||||||
| Metadata Last Modified: | 27 May 2021 13:51 |
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