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Altitudinal Heterogeneity of UV Adaptation in Phytophthora infestans Is Associated with the Spatial Distribution of a DNA Repair Gene

Wang, Yan-Ping and Waheed, Abdul and Liu, Shi-Ting and Li, Wen-Yang and Nkurikiyimfura, Oswald and Lurwanu, Yahuza and Wang, Zonghua and Grenville-Briggs Didymus, Laura and Yang, Lina and Zheng, Luping and Zhan, Jiasui (2021). Altitudinal Heterogeneity of UV Adaptation in Phytophthora infestans Is Associated with the Spatial Distribution of a DNA Repair Gene. Journal of Fungi. 7 , 245
[Research article]

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Abstract

Climate change is considered a major threat to society and nature. UV irradiation is the most important environmental genotoxic agent. Thus, how elevated UV irradiation may influence human health and ecosystems has generated wide concern in the scientific community, as well as with policy makers and the public in general. In this study, we investigated patterns and mechanisms of UV adaptation in natural ecosystems by studying a gene-specific variation in the potato late blight pathogen, Phytophthora infestans. We compared the sequence characteristics of radiation sensitive 23 (RAD23), a gene involved in the nucleotide excision repair (NER) pathway and UV tolerance, in P. infestans isolates sampled from various altitudes. We found that lower genetic variation in the RAD23 gene was caused by natural selection. The hypothesis that UV irradiation drives this selection was supported by strong correlations between the genomic characteristics and altitudinal origin (historic UV irradiation) of the RAD23 sequences with UV tolerance of the P. infestans isolates. These results indicate that the RAD23 gene plays an important role in the adaptation of P. infestans to UV stress. We also found that different climatic factors could work synergistically to determine the evolutionary adaptation of species, making the influence of climate change on ecological functions and resilience more difficult to predict. Future attention should aim at understanding the collective impact generated by simultaneous change in several climate factors on species adaptation and ecological sustainability, using state of the art technologies such as experimental evolution, genome-wide scanning, and proteomics.

Authors/Creators:Wang, Yan-Ping and Waheed, Abdul and Liu, Shi-Ting and Li, Wen-Yang and Nkurikiyimfura, Oswald and Lurwanu, Yahuza and Wang, Zonghua and Grenville-Briggs Didymus, Laura and Yang, Lina and Zheng, Luping and Zhan, Jiasui
Title:Altitudinal Heterogeneity of UV Adaptation in Phytophthora infestans Is Associated with the Spatial Distribution of a DNA Repair Gene
Series Name/Journal:Journal of Fungi
Year of publishing :2021
Volume:7
Article number:245
Number of Pages:17
Publisher:MDPI
Language:English
Publication Type:Research article
Article category:Scientific peer reviewed
Version:Published version
Copyright:Creative Commons: Attribution 4.0
Full Text Status:Public
Subjects:(A) Swedish standard research categories 2011 > 4 Agricultural Sciences > 401 Agricultural, Forestry and Fisheries > Agricultural Science
(A) Swedish standard research categories 2011 > 1 Natural sciences > 106 Biological Sciences (Medical to be 3 and Agricultural to be 4) > Microbiology (Microbiology in the medical area to be 30109)
Keywords:population genomics, UV adaptation, purifying selection, ecological sustainability, climate change, DNA repair gene
URN:NBN:urn:nbn:se:slu:epsilon-p-111992
Permanent URL:
http://urn.kb.se/resolve?urn=urn:nbn:se:slu:epsilon-p-111992
Additional ID:
Type of IDID
DOI10.3390/jof7040245
Web of Science (WoS)000643116000001
ID Code:23922
Faculty:LTV - Fakulteten för landskapsarkitektur, trädgårds- och växtproduktionsvetenskap
NJ - Fakulteten för naturresurser och jordbruksvetenskap
Department:(LTJ, LTV) > Department of Plant Protection Biology
(NL, NJ) > Dept. of Forest Mycology and Plant Pathology
(S) > Dept. of Forest Mycology and Plant Pathology
Deposited By: SLUpub Connector
Deposited On:27 May 2021 14:03
Metadata Last Modified:27 May 2021 14:11

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