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Sindbis virus neutralising antibodies detected in Swedish horses

Bjornstrom, Agnes and Blomström, Anne-Lie and Singh, Manish Chandra and Hesson, Jenny C. (2021). Sindbis virus neutralising antibodies detected in Swedish horses. One Health. 12 , 100242
[Research article]

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Abstract

A number of viruses transmitted by mosquitoes are well known to cause disease in both humans and horses, ranging from mild fevers to mortal neurological disease. A recently discovered connection between the alphavirus Sindbis virus (SINV) and neurological disease in horses in South Africa initiated this serological study in northern Europe, where the same genotype of SINV (SINV-I) is also highly endemic. We tested 171 serum samples, originally obtained from horses for other reasons from April to October 2019, for presence of SINV neutralising antibodies using a plaque reduction neutralisation test (PRNT). The serum from six horses reduced the plaque count more than 80%, and two out of these reduced the plaque count more than 90%. These horses were sampled in six different regions of Sweden, and included individuals sampled from April to August. This study shows that horses in Sweden have become infected with SINV and developed neutralising antibodies. Potential connections between infection and development of disease are important questions for future studies.

Authors/Creators:Bjornstrom, Agnes and Blomström, Anne-Lie and Singh, Manish Chandra and Hesson, Jenny C.
Title:Sindbis virus neutralising antibodies detected in Swedish horses
Series Name/Journal:One Health
Year of publishing :2021
Volume:12
Article number:100242
Number of Pages:5
Publisher:ELSEVIER
Language:English
Publication Type:Research article
Article category:Scientific peer reviewed
Version:Published version
Copyright:Creative Commons: Attribution 4.0
Full Text Status:Public
Subjects:(A) Swedish standard research categories 2011 > 4 Agricultural Sciences > 403 Veterinary Science > Clinical Science
Keywords:Alphavirus, Serology, Equine encephalitis, Equine fever, Arbovirus, Neutralisation test
URN:NBN:urn:nbn:se:slu:epsilon-p-112090
Permanent URL:
http://urn.kb.se/resolve?urn=urn:nbn:se:slu:epsilon-p-112090
Additional ID:
Type of IDID
DOI10.1016/j.onehlt.2021.100242
Web of Science (WoS)000647609500015
ID Code:24405
Faculty:VH - Faculty of Veterinary Medicine and Animal Science
Department:(VH) > Department of Biomedical Science and Veterinary Public Health
Deposited By: SLUpub Connector
Deposited On:07 Jun 2021 06:23
Metadata Last Modified:07 Jun 2021 06:31

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