Home About Browse Search
Svenska


Experimental inoculation of Treponema pedis T A4 failed to induce ear necrosis in pigs

Karlsson, Frida and Rosander, Anna and Fellström, Claes and Backhans, Annette (2017). Experimental inoculation of Treponema pedis T A4 failed to induce ear necrosis in pigs. Porcine Health Management. 3 , 26
[Research article]

[img] PDF
533kB

Abstract

Ear necrosis is a syndrome affecting pigs shortly after weaning and is regarded as an animal welfare issue. The etiology is unknown but Treponema spp., predominantly Treponema pedis, are commonly detected in the lesions. Oral treponemes have been suggested as source of infection, transferred by biting and licking behavior. In this study, five pigs were intradermally inoculated with Treponema pedis strain T A4 with the aim of investigating if this strain would induce ear lesions. Three pigs served as controls. The inoculation was repeated after 29 days, and the study continued for 56 days. Serum samples were collected throughout the study and analyzed by ELISA for IgG antibodies towards T. pedis T A4 lysate. Skin biopsies were taken from the inoculation area at the end of the study. Gingival samples were collected and cultivated for treponemes, for comparison to the inoculation strain and to follow colonisation. The challenged pigs did not develop any clinical signs of infection and no spirochetes were detected in sections from skin biopsies. The number of Treponema-positive gingival samples increased during the study. In the challenge group, IgG towards the bacterial lysate peaked 7 days after each inoculation and decreased rapidly hereafter. In the control group a weak IgG response was observed after the second inoculation, possibly caused by the oral treponemes.

Authors/Creators:Karlsson, Frida and Rosander, Anna and Fellström, Claes and Backhans, Annette
Title:Experimental inoculation of Treponema pedis T A4 failed to induce ear necrosis in pigs
Series Name/Journal:Porcine Health Management
Year of publishing :2017
Volume:3
Article number:26
Number of Pages:5
Publisher:BMC
ISSN:2055-5660
Language:English
Publication Type:Research article
Article category:Scientific peer reviewed
Version:Published version
Copyright:Creative Commons: Attribution 4.0
Full Text Status:Public
Subjects:(A) Swedish standard research categories 2011 > 4 Agricultural Sciences > 403 Veterinary Science > Clinical Science
Keywords:Pig, Ear necrosis, Treponema, IgG, Experimental infection
URN:NBN:urn:nbn:se:slu:epsilon-p-112499
Permanent URL:
http://urn.kb.se/resolve?urn=urn:nbn:se:slu:epsilon-p-112499
Additional ID:
Type of IDID
DOI10.1186/s40813-017-0073-2
Web of Science (WoS)000427794200001
ID Code:24666
Faculty:VH - Faculty of Veterinary Medicine and Animal Science
Department:(VH) > Department of Biomedical Science and Veterinary Public Health
(VH) > Dept. of Clinical Sciences
Deposited By: SLUpub Connector
Deposited On:22 Jun 2021 14:03
Metadata Last Modified:22 Jun 2021 14:11

Repository Staff Only: item control page

Downloads

Downloads per year (since September 2012)

View more statistics

Downloads
Hits