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Risk factors for severe postoperative complications in dogs with cranial cruciate ligament disease-A survival analysis

Engdahl, Karolina and Boge, Gudrun S. and Bergström, Annika and Moldal, Elena R. and Höglund, Odd (2021). Risk factors for severe postoperative complications in dogs with cranial cruciate ligament disease-A survival analysis. Preventive Veterinary Medicine. 191 , 105350
[Research article]

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Abstract

Objective: To analyze the effect of surgical technique and other risk factors on severe postoperative complications in dogs with cranial cruciate ligament disease (CCLD). Materials and Methods: A cohort study of 255 dogs (287 stifles) surgically treated for CCLD at two veterinary university hospitals (2011 & ndash;2016) was performed. The electronic medical records were reviewed and dog owners and referring veterinarians contacted for additional information. The complications were classified as minor, major and catastrophic, where major and catastrophic were considered severe. A multivariable Cox proportional hazards model was applied to assess risk factors for severe postoperative complications.Results: Three surgical techniques were used; lateral fabellotibial suture (LFS, 141 stifles), tibial plateau leveling osteotomy (TPLO, 77 stifles) and tibial tuberosity advancement (TTA, 69 stifles). The most common severe postoperative complications were surgical site infections or complications related to the surgical implant. Severe postoperative complications occurred in 31 % of the stifles treated with TPLO, 22 % of the stifles treated with LFS and 25 % of the stifles treated with TTA. The multivariable Cox proportional hazards model identified surgical technique (p = 0.0258) as a risk factor for severe postoperative complications; TPLO had a significantly lower hazard than LFS (hazard ratio (HR) = 0.37, p = 0.007) when controlling for body weight and age, which also were identified as risk factors (HR = 1.05, p < 0.001 and HR = 0.91, p = 0.047, respectively).Conclusion and Clinical relevance: Although TPLO procedures had the highest occurrence of severe postoperative complications, the hazard was lower than for LFS after adjusting for body weight and age. This implies that it is important to consider potential effect-modifiers when comparing postoperative complications after CCLD surgery.

Authors/Creators:Engdahl, Karolina and Boge, Gudrun S. and Bergström, Annika and Moldal, Elena R. and Höglund, Odd
Title:Risk factors for severe postoperative complications in dogs with cranial cruciate ligament disease-A survival analysis
Series Name/Journal:Preventive Veterinary Medicine
Year of publishing :2021
Volume:191
Article number:105350
Number of Pages:8
Publisher:ELSEVIER
ISSN:0167-5877
Language:English
Publication Type:Research article
Article category:Scientific peer reviewed
Version:Published version
Copyright:Creative Commons: Attribution-Noncommercial-No Derivative Works 4.0
Full Text Status:Public
Subjects:(A) Swedish standard research categories 2011 > 4 Agricultural Sciences > 403 Veterinary Science > Clinical Science
Keywords:Orthopedic, Stifle surgery, Canine, Risk factor, Lameness, Survival analysis, SSI, Epidemiology
URN:NBN:urn:nbn:se:slu:epsilon-p-112555
Permanent URL:
http://urn.kb.se/resolve?urn=urn:nbn:se:slu:epsilon-p-112555
Additional ID:
Type of IDID
DOI10.1016/j.prevetmed.2021.105350
Web of Science (WoS)000653029700007
ID Code:24737
Faculty:VH - Faculty of Veterinary Medicine and Animal Science
Department:(VH) > Dept. of Clinical Sciences
Deposited By: SLUpub Connector
Deposited On:28 Jun 2021 14:25
Metadata Last Modified:28 Jun 2021 14:31

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