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Seroepidemiology of Crimean-Congo hemorrhagic fever virus (CCHFV) –in cattle across three livestock pastoral regions in Kenya

Blanco Penedo, Isabel and Obanda, Vincent and Kingori, Edward and Agwanda, Bernard and Ahlm, Clas and Lwande, Olivia Wesula (2021). Seroepidemiology of Crimean-Congo hemorrhagic fever virus (CCHFV) –in cattle across three livestock pastoral regions in Kenya. Dairy. 2 , 425-434
[Research article]

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Abstract

Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne zoonotic disease, endemic in Africa, with a high case fatality rate. There is no efficient treatment or licensed vaccine. This study aimed to determine the prevalence of CCHFV in cattle in extensive grazing systems (both pastoralism and ranching) within the Maasai Mara ecosystem, Nanyuki, and the Ol Pejeta Conservancy in Kenya. We conducted a seroepidemiological study of the sera of 148 cattle from 18 households from the three ecosystems in 2014, 2016, and 2019. Sera from 23 sheep and 17 goats were also obtained from the same households during the same period. Sera were analyzed for the presence of antibodies to CCHFV using the commercially available double-antigen ELISA kit. Overall, 31.5% CCHFV seropositivity was observed. The prevalence of CCHF was analyzed using a multiple logistic mixed model with main predictors. Risk factors associated with exposure to CCHFV were age (p = 0.000) and season (p = 0.007). Our findings suggest exposure to CCHFV and point to cattle as likely reservoirs of CCHFV in Kenya. The findings might play a role in providing better insights into disease risk and dynamics where analysis of tick populations in these regions should be further investigated.

Authors/Creators:Blanco Penedo, Isabel and Obanda, Vincent and Kingori, Edward and Agwanda, Bernard and Ahlm, Clas and Lwande, Olivia Wesula
Title:Seroepidemiology of Crimean-Congo hemorrhagic fever virus (CCHFV) –in cattle across three livestock pastoral regions in Kenya
Series Name/Journal:Dairy
Year of publishing :2021
Volume:2
Page range:425-434
Number of Pages:10
Language:English
Publication Type:Research article
Article category:Scientific peer reviewed
Version:Published version
Copyright:Creative Commons: Attribution 4.0
Full Text Status:Public
Subjects:(A) Swedish standard research categories 2011 > 4 Agricultural Sciences > 403 Veterinary Science > Clinical Science
Keywords:seroprevalence, vector-borne infections, Crimean-Congo hemorrhagic fever, ruminants, ecosystem, pastoralism, ranching
URN:NBN:urn:nbn:se:slu:epsilon-p-112827
Permanent URL:
http://urn.kb.se/resolve?urn=urn:nbn:se:slu:epsilon-p-112827
Additional ID:
Type of IDID
DOI10.3390/dairy2030034
ID Code:24880
Faculty:VH - Faculty of Veterinary Medicine and Animal Science
Department:(VH) > Dept. of Clinical Sciences
Deposited By: SLUpub Connector
Deposited On:12 Aug 2021 08:25
Metadata Last Modified:12 Aug 2021 08:31

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