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Computed tomography is superior to radiography for detection of feline elbow osteoarthritis

Ley, Charles and Leijon, Alexandra and Uhlhorn, Margareta and Marcelino, Leticia and Hansson, Kerstin and Ley, Cecilia (2021). Computed tomography is superior to radiography for detection of feline elbow osteoarthritis. Research in Veterinary Science. 140 , 6-17
[Research article]

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Abstract

Elbow osteoarthritis (OA) is common in cats and radiography is typically used for diagnosis. However computed tomography (CT), with its multiplanar three-dimensional characteristics, could have significant advantages for assessment of OA compared to radiography, particularly early in the disease process. The study objectives were to compare radiography and CT to histologic OA changes, investigate the stage of OA that radiography and CT detect, and search for specific changes in CT images strongly predictive for feline elbow OA. Right elbows from 29 cats were evaluated by radiography and CT, and articular cartilage lesions graded histologically and macroscopically. Three further joints were sampled to specifically evaluate the morphology of the anconeal process. Macroscopic, radiographic and CT OA diagnosis were compared to the reference standard histologic OA that was divided into mild, moderate and severe. Osteophytic spurs on the lateral margin of the anconeal process could be reliably measured in CT images (intra-class correlation 0.79) and when >= 0.5 mm had high sensitivity for moderate/severe histologic OA, moderate sensitivity for mild histologic OA and high specificity for all stages of OA. In moderate/severe histologic OA both radiography and CT subjective OA diagnosis had moderate to very high sensitivity. However, in mild histologic OA CT grading had low sensitivity and radiography did not detect OA. In conclusion, CT of the feline elbow including measurement of osteophytes on the anconeal process lateral margin is superior to radiography for OA detection and should be considered for OA diagnosis, particularly when mild OA changes are of interest.

Authors/Creators:Ley, Charles and Leijon, Alexandra and Uhlhorn, Margareta and Marcelino, Leticia and Hansson, Kerstin and Ley, Cecilia
Title:Computed tomography is superior to radiography for detection of feline elbow osteoarthritis
Series Name/Journal:Research in Veterinary Science
Year of publishing :2021
Volume:140
Page range:6-17
Number of Pages:12
Publisher:ELSEVIER SCI LTD
ISSN:0034-5288
Language:English
Publication Type:Research article
Article category:Scientific peer reviewed
Version:Published version
Copyright:Creative Commons: Attribution 4.0
Full Text Status:Public
Subjects:(A) Swedish standard research categories 2011 > 4 Agricultural Sciences > 403 Veterinary Science > Clinical Science
Keywords:Anconeal, Cartilage, Cat, Joint, OA, Osteophyte
URN:NBN:urn:nbn:se:slu:epsilon-p-114046
Permanent URL:
http://urn.kb.se/resolve?urn=urn:nbn:se:slu:epsilon-p-114046
Additional ID:
Type of IDID
DOI10.1016/j.rvsc.2021.07.025
Web of Science (WoS)000703894700002
ID Code:25893
Faculty:VH - Faculty of Veterinary Medicine and Animal Science
University Animal Hospital
Department:(VH) > Dept. of Clinical Sciences
(VH) > Department of Biomedical Science and Veterinary Public Health
University Animal Hospital (UAH)
Deposited By: SLUpub Connector
Deposited On:21 Oct 2021 11:25
Metadata Last Modified:21 Oct 2021 11:31

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