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Seminiferous epithelium cycle staging based on the development of the acrosome in ram testis

Sturm, Sabina and Svara, Tanja and Spörndly-Nees, Ellinor and Cerkvenik-Flajs, Vesna and Gombac, Mitja and Weber, Anna-Luisa and Weber, Klaus (2021). Seminiferous epithelium cycle staging based on the development of the acrosome in ram testis. Journal of toxicologic pathology. 34 , 331-338
[Research article]

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Abstract

Testicular histopathology is considered the most sensitive and reliable method to detect the effects of chemicals on sperm production. To carry out a sensitive examination of testicular histopathology and interpret the changes require knowledge of spermatogenic stages. Spermatogenic staging based on acrosome development during spermiogenesis is conventionally performed in animal species routinely used for research and toxicity testing. In contrast, small ruminants, such as sheep and goats, are rarely used as animal models to evaluate toxicity in male reproductive organs. To the best of our knowledge, a comparable spermatogenic staging system in rams has not yet been fully characterised. Hence, this study aimed to adapt the existing spermatogenic staging based on acrosome development in bull testes to fit the seminiferous epithelium cycle of ram testes. The results show that spermatogenic staging based on acrosome development in bull testes can, with slight modifications, be efficiently used for the staging of ram testes.

Authors/Creators:Sturm, Sabina and Svara, Tanja and Spörndly-Nees, Ellinor and Cerkvenik-Flajs, Vesna and Gombac, Mitja and Weber, Anna-Luisa and Weber, Klaus
Title:Seminiferous epithelium cycle staging based on the development of the acrosome in ram testis
Series Name/Journal:Journal of toxicologic pathology
Year of publishing :2021
Volume:34
Page range:331-338
Number of Pages:8
Publisher:JAPANESE SOC TOXICOLOGIC PATHOLOGY
ISSN:0914-9198
Language:English
Publication Type:Research article
Article category:Scientific peer reviewed
Version:Published version
Copyright:Creative Commons: Attribution-Noncommercial-No Derivative Works 4.0
Full Text Status:Public
Subjects:(A) Swedish standard research categories 2011 > 4 Agricultural Sciences > 403 Veterinary Science > Pathobiology
Keywords:ram, spermatogenesis, staging, acrosome development, spermiogenesis
URN:NBN:urn:nbn:se:slu:epsilon-p-114268
Permanent URL:
http://urn.kb.se/resolve?urn=urn:nbn:se:slu:epsilon-p-114268
Additional ID:
Type of IDID
DOI10.1293/tox.2021-0025
Web of Science (WoS)000708062100006
ID Code:26089
Faculty:VH - Faculty of Veterinary Medicine and Animal Science
Department:(VH) > Dept. of Anatomy, Physiology and Biochemistry
Deposited By: SLUpub Connector
Deposited On:11 Nov 2021 13:25
Metadata Last Modified:11 Nov 2021 13:31

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