Rising, Anna and Gherardi, Paola and Chen, Gefei and Johansson, Jan and Oskarsson, Marie E. and Westermark, Gunilla T. and Westermark, Per
(2021).
AA amyloid in human food chain is a possible biohazard.
Scientific Reports. 11
, 21069
[Research article]
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Abstract
AA amyloidosis can be transmitted experimentally in several mammalian and avian species as well as spontaneously between captive animals, even by oral intake of amyloid seeds. Amyloid seeding can cross species boundaries, and fibrils of one kind of amyloid protein may also seed other types. Here we show that meat from Swedish and Italian cattle for consumption by humans often contains AA amyloid and that bovine AA fibrils efficiently cross-seed human amyloid beta peptide, associated with Alzheimer's disease.
| Authors/Creators: | Rising, Anna and Gherardi, Paola and Chen, Gefei and Johansson, Jan and Oskarsson, Marie E. and Westermark, Gunilla T. and Westermark, Per | ||||||
|---|---|---|---|---|---|---|---|
| Title: | AA amyloid in human food chain is a possible biohazard | ||||||
| Series Name/Journal: | Scientific Reports | ||||||
| Year of publishing : | 2021 | ||||||
| Volume: | 11 | ||||||
| Article number: | 21069 | ||||||
| Number of Pages: | 5 | ||||||
| Publisher: | NATURE PORTFOLIO | ||||||
| ISSN: | 2045-2322 | ||||||
| Language: | English | ||||||
| Publication Type: | Research article | ||||||
| Article category: | Scientific peer reviewed | ||||||
| Version: | Published version | ||||||
| Copyright: | Creative Commons: Attribution 4.0 | ||||||
| Full Text Status: | Public | ||||||
| Subjects: | (A) Swedish standard research categories 2011 > 1 Natural sciences > 106 Biological Sciences (Medical to be 3 and Agricultural to be 4) > Biochemistry and Molecular Biology (A) Swedish standard research categories 2011 > 3 Medical and Health Sciences > 301 Basic Medicine > Neurosciences | ||||||
| URN:NBN: | urn:nbn:se:slu:epsilon-p-114384 | ||||||
| Permanent URL: | http://urn.kb.se/resolve?urn=urn:nbn:se:slu:epsilon-p-114384 | ||||||
| Additional ID: |
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| ID Code: | 26180 | ||||||
| Faculty: | VH - Faculty of Veterinary Medicine and Animal Science | ||||||
| Department: | (VH) > Dept. of Anatomy, Physiology and Biochemistry | ||||||
| Deposited By: | SLUpub Connector | ||||||
| Deposited On: | 19 Nov 2021 14:25 | ||||||
| Metadata Last Modified: | 19 Nov 2021 14:31 |
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