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AA amyloid in human food chain is a possible biohazard

Rising, Anna and Gherardi, Paola and Chen, Gefei and Johansson, Jan and Oskarsson, Marie E. and Westermark, Gunilla T. and Westermark, Per (2021). AA amyloid in human food chain is a possible biohazard. Scientific Reports. 11 , 21069
[Research article]

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Abstract

AA amyloidosis can be transmitted experimentally in several mammalian and avian species as well as spontaneously between captive animals, even by oral intake of amyloid seeds. Amyloid seeding can cross species boundaries, and fibrils of one kind of amyloid protein may also seed other types. Here we show that meat from Swedish and Italian cattle for consumption by humans often contains AA amyloid and that bovine AA fibrils efficiently cross-seed human amyloid beta peptide, associated with Alzheimer's disease.

Authors/Creators:Rising, Anna and Gherardi, Paola and Chen, Gefei and Johansson, Jan and Oskarsson, Marie E. and Westermark, Gunilla T. and Westermark, Per
Title:AA amyloid in human food chain is a possible biohazard
Series Name/Journal:Scientific Reports
Year of publishing :2021
Volume:11
Article number:21069
Number of Pages:5
Publisher:NATURE PORTFOLIO
ISSN:2045-2322
Language:English
Publication Type:Research article
Article category:Scientific peer reviewed
Version:Published version
Copyright:Creative Commons: Attribution 4.0
Full Text Status:Public
Subjects:(A) Swedish standard research categories 2011 > 1 Natural sciences > 106 Biological Sciences (Medical to be 3 and Agricultural to be 4) > Biochemistry and Molecular Biology
(A) Swedish standard research categories 2011 > 3 Medical and Health Sciences > 301 Basic Medicine > Neurosciences
URN:NBN:urn:nbn:se:slu:epsilon-p-114384
Permanent URL:
http://urn.kb.se/resolve?urn=urn:nbn:se:slu:epsilon-p-114384
Additional ID:
Type of IDID
DOI10.1038/s41598-021-00588-w
Web of Science (WoS)000711622600096
ID Code:26180
Faculty:VH - Faculty of Veterinary Medicine and Animal Science
Department:(VH) > Dept. of Anatomy, Physiology and Biochemistry
Deposited By: SLUpub Connector
Deposited On:19 Nov 2021 14:25
Metadata Last Modified:19 Nov 2021 14:31

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