Home About Browse Search
Svenska


Changes to human faecal microbiota after international travel

Kampmann, Christian and Dicksved, Johan and Engstrand, Lars and Rautelin, Hilpi (2021). Changes to human faecal microbiota after international travel. Travel Medicine and Infectious Disease. 44 , 102199
[Research article]

[img] PDF
676kB

Abstract

Background: The aim was to investigate whether travelling to less-resourced destinations influences the composition of faecal microbiota in generally healthy adults. Method: In this prospective observational study, 47 adults (median age, 24 years; 73% females) travelled from Sweden to distant destinations for 1-12 weeks. Five faecal samples, two before and three after travel, were analysed by 16S amplicon massive parallel sequencing. Subjects had taken no antibiotics within three months of each sampling. Results: The overall composition of faecal microbiota was not affected by travel. However, when looking at the relative abundance of individual bacterial taxa, Enterobacteriaceae demonstrated a 10-fold increase immediately after the trip as compared to the samples taken before travelling. Conversely, the relative abundance of Chris-tensenellaceae had decreased equally much. Both these changes were reversible within nine weeks. Conclusions: International travel, even to less-resourced countries, did not appear to alter the overall diversity of human faecal microbiota as studied here after travelling. However, Enterobacteriaceae bacteria, often associated with infection, inflammation, and antibiotic resistance, showed dramatically elevated levels, and Christense-nellaceae, frequently associated with healthy conditions, demonstrated remarkably declined levels in relative abundance as detected immediately after travel. Both these changes returned to original pre-travel levels within nine weeks.

Authors/Creators:Kampmann, Christian and Dicksved, Johan and Engstrand, Lars and Rautelin, Hilpi
Title:Changes to human faecal microbiota after international travel
Series Name/Journal:Travel Medicine and Infectious Disease
Year of publishing :2021
Volume:44
Article number:102199
Number of Pages:7
Publisher:ELSEVIER SCI LTD
ISSN:1477-8939
Language:English
Publication Type:Research article
Article category:Scientific peer reviewed
Version:Published version
Copyright:Creative Commons: Attribution 4.0
Full Text Status:Public
Subjects:(A) Swedish standard research categories 2011 > 3 Medical and Health Sciences > 302 Clinical Medicine > Infectious Medicine
Keywords:Human faecal microbiota, Travel, Enterobacteriaceae, Christensenellaceae
URN:NBN:urn:nbn:se:slu:epsilon-p-114550
Permanent URL:
http://urn.kb.se/resolve?urn=urn:nbn:se:slu:epsilon-p-114550
Additional ID:
Type of IDID
DOI10.1016/j.tmaid.2021.102199
Web of Science (WoS)000720450000002
ID Code:26282
Faculty:VH - Faculty of Veterinary Medicine and Animal Science
Department:(VH) > Dept. of Animal Nutrition and Management
Deposited By: SLUpub Connector
Deposited On:07 Dec 2021 08:25
Metadata Last Modified:07 Dec 2021 08:31

Repository Staff Only: item control page

Downloads

Downloads per year (since September 2012)

View more statistics

Downloads
Hits