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Continuous gastric saline perfusion elicits cardiovascular responses in freshwater rainbow trout (Oncorhynchus mykiss)

Morgenroth, Daniel and McArley, Tristan and Ekstrom, Andreas and Gräns, Albin and Axelsson, Michael and Sandblom, Erik (2022). Continuous gastric saline perfusion elicits cardiovascular responses in freshwater rainbow trout (Oncorhynchus mykiss). Journal of Comparative Physiology B :: Biochemical, Systemic, and Environmental Physiology. 192 :1 , 95-106
[Research article]

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Abstract

When in seawater, rainbow trout (Oncorhynchus mykiss) drink to avoid dehydration and display stroke volume (SV) mediated elevations in cardiac output (CO) and an increased proportion of CO is diverted to the gastrointestinal tract as compared to when in freshwater. These cardiovascular alterations are associated with distinct reductions in systemic and gastrointestinal vascular resistance (R-Sys and R-GI, respectively). Although increased gastrointestinal blood flow (GBF) is likely essential for osmoregulation in seawater, the sensory functions and mechanisms driving the vascular resistance changes and other associated cardiovascular changes in euryhaline fishes remain poorly understood. Here, we examined whether internal gastrointestinal mechanisms responsive to osmotic changes mediate the cardiovascular changes typically observed in seawater, by comparing the cardiovascular responses of freshwater-acclimated rainbow trout receiving continuous (for 4 days) gastric perfusion with half-strength seawater (1/2 SW, similar to 17 ppt) to control fish (i.e., no perfusion). We show that perfusion with 1/2 SW causes significantly larger increases in CO, SV and GBF, as well as reductions in R-Sys and R-GI, compared with the control, whilst there were no significant differences in blood composition between treatments. Taken together, our data suggest that increased gastrointestinal luminal osmolality is sensed directly in the gut, and at least partly, mediates cardiovascular responses previously observed in SW acclimated rainbow trout. Even though a potential role of mechano-receptor stimulation from gastrointestinal volume loading in eliciting these cardiovascular responses cannot be excluded, our study indicates the presence of internal gastrointestinal milieu-sensing mechanisms that affect cardiovascular responses when environmental salinity changes.

Authors/Creators:Morgenroth, Daniel and McArley, Tristan and Ekstrom, Andreas and Gräns, Albin and Axelsson, Michael and Sandblom, Erik
Title:Continuous gastric saline perfusion elicits cardiovascular responses in freshwater rainbow trout (Oncorhynchus mykiss)
Series Name/Journal:Journal of Comparative Physiology B :: Biochemical, Systemic, and Environmental Physiology
Year of publishing :2022
Volume:192
Number:1
Page range:95-106
Number of Pages:12
Publisher:SPRINGER HEIDELBERG
ISSN:0174-1578
Language:English
Publication Type:Research article
Article category:Scientific peer reviewed
Version:Published version
Copyright:Creative Commons: Attribution 4.0
Full Text Status:Public
Subjects:(A) Swedish standard research categories 2011 > 4 Agricultural Sciences > 401 Agricultural, Forestry and Fisheries > Fish and Aquacultural Science
Keywords:Gastrointestinal sensing mechanisms, Vascular resistance, Blood flow, Salinity
URN:NBN:urn:nbn:se:slu:epsilon-p-114052
Permanent URL:
http://urn.kb.se/resolve?urn=urn:nbn:se:slu:epsilon-p-114052
Additional ID:
Type of IDID
DOI10.1007/s00360-021-01408-3
Web of Science (WoS)000704934400001
ID Code:27102
Faculty:VH - Faculty of Veterinary Medicine and Animal Science
Department:(VH) > Dept. of Animal Environment and Health
Deposited By: SLUpub Connector
Deposited On:14 Feb 2022 16:25
Metadata Last Modified:14 Feb 2022 16:31

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