Home About Browse Search
Svenska


Application of a novel prioritisation strategy using non-target screening for evaluation of temporal trends (1969-2017) of contaminants of emerging concern (CECs) in archived lynx muscle tissue samples

Dürig, Wiebke and Durig, Wiebke and Alygizakis, Nikiforos A. and Wiberg, Karin and Ahrens, Lutz (2022). Application of a novel prioritisation strategy using non-target screening for evaluation of temporal trends (1969-2017) of contaminants of emerging concern (CECs) in archived lynx muscle tissue samples. Science of the Total Environment. 817 , 153035
[Research article]

[img] PDF
959kB

Abstract

Most environmental monitoring studies of contaminants of emerging concern (CECs) focus on aquatic species and target specific classes of CECs. Even with wide-scope target screening methods, relevant CECs may be missed. In this study, non-target screening (NTS) was used for tentative identification of potential CECs in muscle tissue of the terrestrial top predator Eurasian lynx (Lynx lynx). Temporal trend analysis was applied as a prioritisation tool for archived samples, using univariate statistical tests (Mann-Kendall and Spearman rank). Pooled lynx muscle tissue collected from 1969 to 2017 was analysed with an eight-point time series using a previously validated screening workflow. Following peak detection, peak alignment, and blank subtraction, 12,941 features were considered for statistical analysis. Prioritisation by time-trend analysis detected 104 and 61 features with statistically significant increasing and decreasing trends, respectively. Following probable molecular formula assignment and elucidation with MetFrag, two compounds with increasing trends, and one with a decreasing trend, were tentatively identified. These results show that, despite low expected concentration levels and high matrix effects in terrestrial species, it is possible to prioritise CECs in archived lynx samples using NTS and univariate statistical approaches.

Authors/Creators:Dürig, Wiebke and Durig, Wiebke and Alygizakis, Nikiforos A. and Wiberg, Karin and Ahrens, Lutz
Title:Application of a novel prioritisation strategy using non-target screening for evaluation of temporal trends (1969-2017) of contaminants of emerging concern (CECs) in archived lynx muscle tissue samples
Series Name/Journal:Science of the Total Environment
Year of publishing :2022
Volume:817
Article number:153035
Number of Pages:8
Publisher:ELSEVIER
ISSN:0048-9697
Language:English
Publication Type:Research article
Article category:Scientific peer reviewed
Version:Published version
Copyright:Creative Commons: Attribution-Noncommercial-No Derivative Works 4.0
Full Text Status:Public
Subjects:(A) Swedish standard research categories 2011 > 1 Natural sciences > 105 Earth and Related Environmental Sciences > Environmental Sciences (social aspects to be 507)
Keywords:Non-target analysis, Environmental specimen bank, lynx, LC-QToF-MS, Temporal trend analysis
URN:NBN:urn:nbn:se:slu:epsilon-p-116549
Permanent URL:
http://urn.kb.se/resolve?urn=urn:nbn:se:slu:epsilon-p-116549
Additional ID:
Type of IDID
DOI10.1016/j.scitotenv.2022.153035
Web of Science (WoS)000766810700013
ID Code:27481
Faculty:NJ - Fakulteten för naturresurser och jordbruksvetenskap
Department:(NL, NJ) > Dept. of Aquatic Sciences and Assessment
Deposited By: SLUpub Connector
Deposited On:31 Mar 2022 10:25
Metadata Last Modified:31 Mar 2022 10:31

Repository Staff Only: item control page

Downloads

Downloads per year (since September 2012)

View more statistics

Downloads
Hits