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Transcriptional responses are oriented towards different components of the rearing environment in two Drosophila sibling species

De Panis, D. and Dopazo, H. and Bongcam-Rudloff, Erik and Conesa, A. and Hasson, E. (2022). Transcriptional responses are oriented towards different components of the rearing environment in two Drosophila sibling species. BMC Genomics. 23 , 515
[Research article]

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Abstract

Background The chance to compare patterns of differential gene expression in related ecologically distinct species can be particularly fruitful to investigate the genetics of adaptation and phenotypic plasticity. In this regard, a powerful technique such as RNA-Seq applied to ecologically amenable taxa allows to address issues that are not possible in classic model species. Here, we study gene expression profiles and larval performance of the cactophilic siblings Drosophila buzzatii and D. koepferae reared in media that approximate natural conditions and evaluate both chemical and nutritional components of the diet. These closely related species are complementary in terms of host-plant use since the primary host of one is the secondary of the other. D. koepferae is mainly a columnar cactus dweller while D. buzzatii prefers Opuntia hosts. Results Our comparative study shows that D. buzzatii and D. koepferae have different transcriptional strategies to face the challenges posed by their natural resources. The former has greater transcriptional plasticity, and its response is mainly modulated by alkaloids of its secondary host, while the latter has a more canalized genetic response, and its transcriptional plasticity is associated with the cactus species. Conclusions Our study unveils a complex pleiotropic genetic landscape in both species, with functional links that relate detox responses and redox mechanisms with developmental and neurobiological processes. These results contribute to deepen our understanding of the role of host plant shifts and natural stress driving ecological specialization.

Authors/Creators:De Panis, D. and Dopazo, H. and Bongcam-Rudloff, Erik and Conesa, A. and Hasson, E.
Title:Transcriptional responses are oriented towards different components of the rearing environment in two Drosophila sibling species
Series Name/Journal:BMC Genomics
Year of publishing :2022
Volume:23
Article number:515
Number of Pages:15
Publisher:BMC
ISSN:1471-2164
Language:English
Publication Type:Research article
Article category:Scientific peer reviewed
Version:Published version
Copyright:Creative Commons: Attribution 4.0
Full Text Status:Public
Subjects:(A) Swedish standard research categories 2011 > 1 Natural sciences > 106 Biological Sciences (Medical to be 3 and Agricultural to be 4) > Evolutionary Biology
(A) Swedish standard research categories 2011 > 1 Natural sciences > 106 Biological Sciences (Medical to be 3 and Agricultural to be 4) > Zoology
Keywords:Comparative transcriptomics, Adaptation, Plasticity, Drosophila, Mescaline
URN:NBN:urn:nbn:se:slu:epsilon-p-118433
Permanent URL:
http://urn.kb.se/resolve?urn=urn:nbn:se:slu:epsilon-p-118433
Additional ID:
Type of IDID
DOI10.1186/s12864-022-08745-9
Web of Science (WoS)000826012500001
ID Code:28507
Faculty:VH - Faculty of Veterinary Medicine and Animal Science
Department:(VH) > Dept. of Animal Breeding and Genetics
Deposited By: SLUpub Connector
Deposited On:22 Aug 2022 08:25
Metadata Last Modified:22 Aug 2022 08:31

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