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Trace elements in adolescents

Barany, Ebba (2002). Trace elements in adolescents. Diss. (sammanfattning/summary) Uppsala : Sveriges lantbruksuniv., Acta Universitatis Agriculturae Sueciae. Veterinaria, 1401-6257 ; 117
ISBN 91-576-6354-8
[Doctoral thesis]

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The major aim of the thesis was to monitor toxic and essential trace elements in a cohort of adolescents by blood and serum analyses, and describe the impact of different factors on the element concentrations. The adolescents were from the Swedish cities Uppsala and Trollhättan which represent different socioeconomic and environmental conditions, and were investigated at age 15 and 17. It was shown that an inductively coupled plasma mass spectrometry method was suitable for simultaneous determination of 13 elements in blood or serum. The elements were cobalt, copper, zinc, selenium, rubidium, rhodium, palladium, cadmium, tungsten, platinum, mercury, thallium, and lead. The concentrations of the toxic elements cadmium, mercury and lead were low in the adolescents. Cadmium in blood was strongly positively influenced by smoking habits and by the mother’s education. In contrast to smokers, blood cadmium in non-smokers did not increase between the sampling at age 15 and that at 17. The blood lead was one of the lowest reported and decreased about 10% between the samplings, perhaps due to temporal changes in environmental exposure, or a dilution of body burden in the growing adolescents. Consumption of fish with dietary restrictions due to elevated mercury levels and other, ”non-restricted”, fish predicted blood mercury. Blood mercury also increased with fish consumption in those who consumed only non-restricted fish. Mercury in serum was predicted by dental amalgam, consumption of non-restricted fish, and selenium concentrations. The levels of the essential elements cobalt, copper, zinc and selenium in blood and serum were within the reference intervals, and were not influenced by socioeconomic status. However, age, gender, and residential area had significant influences on the levels, differently for different elements. Fish consumption did not influence selenium concentrations. A large part of the analytical data for rhodium, palladium, platinum and thallium were below the detection limits, thus restricting the interpretation of the results. There were increases in the levels of rhodium, palladium and platinum in serum, as the mean concentrations of these elements were above the detection limits at age 17 but not at age 15.

Authors/Creators:Barany, Ebba
Title:Trace elements in adolescents
Series Name/Journal:Acta Universitatis Agriculturae Sueciae. Veterinaria
Year of publishing :April 2002
Number of Pages:53
ALLI. Ebba Bárány, Ingvar A. Bergdahl, Andrejs Schütz, Staffan Skerfving and Agneta Oskarsson. Inductively coupled plasma mass spectrometry for direct multi-element analysis of diluted human blood and serum. Journal of Analytical Atomic Spectrometry. 1997, 12, 1005-1009. II. Ebba Bárány, Ingvar A. Bergdahl, Lars-Eric Bratteby, Thomas Lundh, Gösta Samuelson, Andrejs Schütz, Staffan Skerfving, Agneta Oskarsson. Trace element levels in whole blood and serum from Swedish adolescents. The Science of the Total Environment, 2002, 286, 129-141. III. Ebba Bárány, Ingvar A. Bergdahl, Lars-Eric Bratteby, Thomas Lundh, Gösta Samuelson, Andrejs Schütz, Staffan Skerfving, Agneta Oskarsson. Trace elements in Swedish adolescents: influence of age, gender, residential area, and socio-economic status. Environmental Research, 2002, 89, 72-84. IV. Ebba Bárány, Ingvar A. Bergdahl, Lars-Eric Bratteby, Thomas Lundh, Gösta Samuelson, Staffan Skerfving, Agneta Oskarsson. Mercury and selenium in whole blood and serum in relation to fish consumption and amalgam fillings in adolescents. Journal of Trace Elements in Medicine and Biology, 2004, 17, 165-170.
Place of Publication:Uppsala
ISBN for printed version:91-576-6354-8
Publication Type:Doctoral thesis
Full Text Status:Public
Agris subject categories.:X Agricola extesions > X38 Human medicine, health, and safety
Subjects:Not in use, please see Agris categories
Agrovoc terms:trace elements, heavy metals, toxicity, human diseases, health, health hazards, youth, human behaviour, fish, food consumption, sweden
Keywords:Blood, dental amalgam fillings, essential elements, fish consumption, ICP-MS, serum, smoking, Sweden, toxic elements
Permanent URL:
ID Code:510
Department:(VH) > Institutionen för farmakologi och toxikologi
Deposited By: Ebba Barany
Deposited On:13 Apr 2004 00:00
Metadata Last Modified:02 Dec 2014 10:05

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